The cross sections of inelastic interaction of 22Ne with C, Al, Cu and Pb targets have been measured at an incident momentum of 4.1 GeV/c per nucleon. The following results have been obtained: 1060 +- 50 mb; 1520 +- 70 mb; 2150 +- 100 mb and 3900 +- 200 mb, respectively. The approximation of the dependence of the cross sections on the mass numbers of interacting nuclei and the measurement procedure are presented
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