The inclusive and fiducial $t\bar{t}$ production cross-sections are measured in the lepton+jets channel using 20.2 fb$^{-1}$ of proton-proton collision data at a centre-of-mass energy of 8 TeV recorded with the ATLAS detector at the LHC. Major systematic uncertainties due to the modelling of the jet energy scale and $b$-tagging efficiency are constrained by separating selected events into three disjoint regions. In order to reduce systematic uncertainties in the most important background, the W+jets process is modelled using Z+jets events in a data-driven approach. The inclusive $t\bar{t}$ cross-section is measured with a precision of 5.7% to be $\sigma_{\text{inc}}(t\bar{t})$ = 248.3 $\pm$ 0.7 (stat.) $\pm$ 13.4 (syst.) $\pm$ 4.7 (lumi.) pb, assuming a top-quark mass of 172.5 GeV. The result is in agreement with the Standard Model prediction. The cross-section is also measured in a phase space close to that of the selected data. The fiducial cross-section is $\sigma_{\text{fid}}(t\bar{t})$ = 48.8 $\pm$ 0.1 (stat.) $\pm$ 2.0 (syst.) $\pm$ 0.9 (lumi.) pb with a precision of 4.5%.
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