The excitation of theΔ resonance is observed in proton collisions on C, Nb and Pb targets at 0.8 and 1.6 GeV incident energies. The mass E0 and widthΓ of the resonance are determined from the invariant mass spectra of correlated (p, π±)-pairs in the final state of the collision: The mass E0 is smaller than that of the free resonance, however by comparing to intra-nuclear cascade calculations, this reduction is traced back to the effects of Fermi motion, NN scattering and pion reabsorption in nuclear matter.