A search for physics beyond the standard model in events with at least three charged leptons (electrons or muons) is presented. The data sample corresponds to an integrated luminosity of 137 fb$^{-1}$ of proton-proton collisions at $\sqrt{s} =$ 13 TeV, collected with the CMS detector at the LHC in 2016-2018. The two targeted signal processes are pair production of type-III seesaw heavy fermions and production of a light scalar or pseudoscalar boson in association with a pair of top quarks. The heavy fermions may be manifested as an excess of events with large values of leptonic transverse momenta or missing transverse momentum. The light scalars or pseudoscalars may create a localized excess in the dilepton mass spectra. The results exclude heavy fermions of the type-III seesaw model for masses below 880 GeV at 95% confidence level in the scenario of equal branching fractions to each lepton flavor. This is the most restrictive limit on the flavor-democratic scenario of the type-III seesaw model to date. Assuming a Yukawa coupling of unit strength to top quarks, branching fractions of new scalar (pseudoscalar) bosons to dielectrons or dimuons above 0.004 (0.03) and 0.04 (0.03) are excluded at 95% confidence level for masses in the range 15-75 and 108-340 GeV, respectively. These are the first limits in these channels on an extension of the standard model with scalar or pseudoscalar particles.

Production cross sections of $\Upsilon$(1S), $\Upsilon$(2S), and $\Upsilon$(3S) states decaying into $\mu^+\mu^-$ in proton-lead (pPb) collisions are reported using data collected by the CMS experiment at $\sqrt{s_\mathrm{NN}} =$ 5.02 TeV. A comparison is made with corresponding cross sections obtained with pp data measured at the same collision energy and scaled by the Pb nucleus mass number. The nuclear modification factor for $\Upsilon$(1S) is found to be $R_\mathrm{pPb}(\Upsilon(1S))$ = 0.806 $\pm$ 0.024 (stat) $\pm$ 0.059 (syst). Similar results for the excited states indicate a sequential suppression pattern, such that $R_\mathrm{pPb}(\Upsilon(1S))$$\gt$$R_\mathrm{pPb}(\Upsilon(2S))$$\gt$$R_\mathrm{pPb}(\Upsilon(3S))$. The suppression is much less pronounced in pPb than in PbPb collisions, and independent of transverse momentum $p_\mathrm{T}^\Upsilon$ and center-of-mass rapidity $y_\mathrm{CM}^\Upsilon$ of the individual $\Upsilon$ state in the studied range $p_\mathrm{T}^\Upsilon$$\lt$ 30 GeV$/c$ and $\vert y_\mathrm{CM}^\Upsilon\vert$$\lt$ 1.93. Models that incorporate sequential suppression of bottomonia in pPb collisions are in better agreement with the data than those which only assume initial-state modifications.

A measurement of the differential cross sections for a W boson produced in association with jets in the muon decay channel is presented. The measurement is based on 13 TeV proton-proton collision data corresponding to an integrated luminosity of 2.2 inverse femtobarns, recorded by the CMS detector at the LHC. The cross sections are reported as functions of jet multiplicity, jet transverse momentum pT, jet rapidity, the scalar pT sum of the jets, and angular correlations between the muon and the jet for different jet multiplicities. The measured cross sections are in agreement with predictions that include multileg leading-order (LO) and next-to-LO matrix element calculations interfaced with parton showers, as well as a next-to-next-to-LO calculation for the W boson and one jet production.

Four-lepton production in proton-proton collisions, $\mathrm{pp}\to (\mathrm{Z}/ \gamma^*)(\mathrm{Z}/\gamma^*) \to 4\ell$, where $\ell = \mathrm{e}$ or $\mu$, is studied at a center-of-mass energy of 13 TeV with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 35.9 fb$^{-1}$. The ZZ production cross section, $\sigma(\mathrm{pp} \to \mathrm{Z}\mathrm{Z}) = 17.2 \pm 0.5\text{ (stat) }\pm 0.7\text{ (syst) }\pm 0.4(\mathrm{theo}) \pm 0.4\text{ (lumi)}$ pb, measured using events with two opposite-sign, same-flavor lepton pairs produced in the mass region $60 < m_{\ell^+\ell^-} < $120 GeV, is consistent with standard model predictions. Differential cross sections are measured and are well described by the theoretical predictions. The Z boson branching fraction to four leptons is measured to be $\mathcal{B}(\mathrm{Z}\to 4\ell) = 4.8 \pm 0.2\text{ (stat) }\pm 0.2\text{ (syst) } \pm 0.1\text{ (theo) }\pm 0.1\text{ (lumi) }\times 10^{-6}$ for events with a four-lepton invariant mass in the range 80 $ < m_{4\ell} < $ 100 GeV and a dilepton mass $m_{\ell\ell} > $4 GeV for all opposite-sign, same-flavor lepton pairs. The results agree with standard model predictions. The invariant mass distribution of the four-lepton system is used to set limits on anomalous ZZZ and ZZ$\gamma$ couplings at 95% confidence level: $-0.0012 < f_4^\mathrm{Z} < 0.0010$, $-0.0010 < f_5^\mathrm{Z} < 0.0013$, $-0.0012 < f_4^{\gamma} < 0.0013$, $-0.0012 < f_5^{\gamma} < 0.0013$.

Differential production cross sections of J/$\psi$ and $\psi$(2S) charmonium and $\Upsilon$(nS) (n = 1, 2, 3) bottomonium states are measured in proton-proton collisions at $\sqrt{s} =$ 13 TeV, with data collected by the CMS detector at the LHC, corresponding to an integrated luminosity of 2.3 fb$^{-1}$ for the J/$\psi$ and 2.7 fb$^{-1}$ for the other mesons. The five quarkonium states are reconstructed in the dimuon decay channel, for dimuon rapidity $|y| <$ 1.2. The double-differential cross sections for each state are measured as a function of $y$ and transverse momentum, and compared to theoretical expectations. In addition, ratios are presented of cross sections for prompt $\psi$(2S) to J/$\psi$, $\Upsilon$(2S) to $\Upsilon$(1S), and $\Upsilon$(3S) to $\Upsilon$(1S) production.

The cross section of top quark pair production is measured in the $\mathrm{t\bar{t}}\to (\ell\nu_{\ell})(\tau_\mathrm{h}\nu_{\tau})\mathrm{b\bar{b}}$ final state, where $\tau_\mathrm{h}$ refers to the hadronic decays of the $\tau$ lepton, and $\ell$ is either an electron or a muon. The data sample corresponds to an integrated luminosity of 35.9 fb$^{-1}$ collected in proton-proton collisions at $\sqrt{s}=$ 13 TeV with the CMS detector. The measured cross section is $\sigma_{\mathrm{t\bar{t}}} =$ 781 $\pm$ 7 (stat) $\pm$ 62 (syst) $\pm$ 20 (lum) pb, and the ratio of the partial width $\Gamma($t$\to\tau\nu_{\tau}$b) to the total decay width of the top quark is measured to be 0.1050 $\pm$ 0.0009 (stat) $\pm$ 0.0071 (syst). This is the first measurement of the $\mathrm{t\bar{t}}$ production cross section in proton-proton collisions at $\sqrt{s}=$ 13 TeV that explicitly includes $\tau$ leptons. The ratio of the cross sections in the $\ell\tau_\mathrm{h}$ and $\ell\ell$ final states yields a value $R_{\ell\tau_\mathrm{h}/\ell\ell}=$ 0.973 $\pm$ 0.009 (stat) $\pm$ 0.066 (syst), consistent with lepton universality.

The cross sections for $\Upsilon$(1S), $\Upsilon$(2S), and $\Upsilon$(3S) production in lead-lead (PbPb) and proton-proton (pp) collisions at $\sqrt{s_{_\mathrm{NN}}} =$ 5.02 TeV have been measured using the CMS detector at the LHC. The nuclear modification factors, R$_\mathrm{AA}$, derived from the PbPb-to-pp ratio of yields for each state, are studied as functions of meson rapidity and transverse momentum, as well as PbPb collision centrality. The yields of all three states are found to be significantly suppressed, and compatible with a sequential ordering of the suppression, R$_\mathrm{AA}$($\Upsilon$(1S)) $>$ R$_\mathrm{AA}$($\Upsilon$(2S)) $>$ R$_\mathrm{AA}$($\Upsilon$(3S)) . The suppression of $\Upsilon$(1S) is larger than that seen at $\sqrt{s_{_\mathrm{NN}}} =$ 2.76 TeV, although the two are compatible within uncertainties. The upper limit on the R$_\mathrm{AA}$ of $\Upsilon$(3S) integrated over $p_\mathrm{T}$ and rapidity is 0.094 at 95% confidence level, which is the strongest suppression observed for any hadron species in heavy ion collisions to date.

Two related searches for phenomena beyond the standard model (BSM) are performed using events with hadronic jets and significant transverse momentum imbalance. The results are based on a sample of proton-proton collisions at a center-of-mass energy of 13 TeV, collected by the CMS experiment at the LHC in 2016-2018 and corresponding to an integrated luminosity of 137 fb$^{-1}$. The first search is inclusive, based on signal regions defined by the hadronic energy in the event, the jet multiplicity, the number of jets identified as originating from bottom quarks, and the value of the kinematic variable $M_\mathrm{T2}$ for events with at least two jets. For events with exactly one jet, the transverse momentum of the jet is used instead. The second search looks in addition for disappearing tracks produced by BSM long-lived charged particles that decay within the volume of the tracking detector. No excess event yield is observed above the predicted standard model background. This is used to constrain a range of BSM models that predict the following: the pair production of gluinos and squarks in the context of supersymmetry models conserving $R$-parity, with or without intermediate long-lived charginos produced in the decay chain; the resonant production of a colored scalar state decaying to a massive Dirac fermion and a quark; or the pair production of scalar and vector leptoquarks each decaying to a neutrino and a top, bottom, or light-flavor quark. In most of the cases, the results obtained are the most stringent constraints to date.

A measurement of the production cross section of top quark pairs in association with two b jets ($\mathrm{t\bar{t}}\mathrm{b\bar{b}}$) is presented using data collected in proton-proton collisions at $\sqrt{s} =$ 13 TeV by the CMS detector at the LHC corresponding to an integrated luminosity of 35.9 fb$^{-1}$. The cross section is measured in the all-jet decay channel of the top quark pair by selecting events containing at least eight jets, of which at least two are identified as originating from the hadronization of b quarks. A combination of multivariate analysis techniques is used to reduce the large background from multijet events not containing a top quark pair, and to help discriminate between jets originating from top quark decays and other additional jets. The cross section is determined for the total phase space to be 5.5 $\pm$ 0.3 (stat)${}^{+1.6}_{-1.3}$ (syst) pb and also measured for two fiducial $\mathrm{t\bar{t}}\mathrm{b\bar{b}}$ definitions. The measured cross sections are found to be larger than theoretical predictions by a factor of 1.5-2.4, corresponding to 1-2 standard deviations.

The nuclear modification factors of J/$\psi$ and $\psi$(2S) mesons are measured in PbPb collisions at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}} =$ 5.02 TeV. The analysis is based on PbPb and pp data samples collected by CMS at the LHC in 2015, corresponding to integrated luminosities of 464 $\mu$b$^{-1}$ and 28 pb$^{-1}$, respectively. The measurements are performed in the dimuon rapidity range of $|y| <$ 2.4 as a function of centrality, rapidity, and transverse momentum (p$_\mathrm{T}$) from p$_\mathrm{T}=$ 3 GeV/$c$ in the most forward region and up to 50 GeV/$c$. Both prompt and nonprompt (coming from b hadron decays) mesons are observed to be increasingly suppressed with centrality, with a magnitude similar to the one observed at $\sqrt{s_{\mathrm{NN}}}=$ 2.76 TeV for the two J/$\psi$ meson components. No dependence on rapidity is observed for either prompt or nonprompt J/$\psi$ mesons. An indication of a lower prompt J/$\psi$ meson suppression at p$_\mathrm{T} >$ 25 GeV/$c$ is seen with respect to that observed at intermediate p$_\mathrm{T}$. The prompt $\psi$(2S) meson yield is found to be more suppressed than that of the prompt J/$\psi$ mesons in the entire p$_\mathrm{T}$ range.