Strong interactions preserve an approximate isospin symmetry between up ($u$) and down ($d$) quarks, part of the more general flavor symmetry. In the case of $K$ meson production, if this isospin symmetry were exact, it would result in equal numbers of charged ($K^+$ and $K^-$) and neutral ($K^0$ and $\overline K^{\,0}$) mesons in the final state. Here, we report results on the relative abundance of charged over neutral $K$ meson production in argon and scandium nuclei collisions at a center-of-mass energy of 11.9 GeV per nucleon pair. We find that the production of $K^+$ and $K^-$ mesons at mid-rapidity is $(18.4\pm 6.1)\%$ higher than that of the neutral $K$ mesons. Although with large uncertainties, earlier data on nucleus-nucleus collisions in the collision center-of-mass energy range $2.6 < \sqrt{s_{NN}} < 200$~\GeV are consistent with the present result. Using well-established models for hadron production, we demonstrate that known isospin-symmetry breaking effects and the initial nuclei containing more neutrons than protons lead only to a small (few percent) deviation of the charged-to-neutral kaon ratio from unity at high energies. Thus, they cannot explain the measurements. The significance of the flavor-symmetry violation beyond the known effects is 4.7$\sigma$ when the compilation of world data with uncertainties quoted by the experiments is used. New systematic, high-precision measurements and theoretical efforts are needed to establish the origin of the observed large isospin-symmetry breaking.
Numerical data for $K^0_S$ from Figure 1.
Numerical data for $K^0_S$ from Figure 1.
Numerical data for $(K^+ + K^-)/2$ from Figure 1.
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