The interpretation of cosmic antiproton flux measurements from space-borne experiments is currently limited by the knowledge of the antiproton production cross-section in collisions between primary cosmic rays and the interstellar medium. Using collisions of protons with an energy of 6.5 TeV incident on helium nuclei at rest in the proximity of the interaction region of the LHCb experiment, the ratio of antiprotons originating from antihyperon decays to prompt production is measured for antiproton momenta between 12 and 110 GeV/c. The dominant antihyperon contribution, namely $\bar{\Lambda} \to \bar{p} \pi^+$ decays from promptly produced $\bar{\Lambda}$ particles, is also exclusively measured. The results complement the measurement of prompt antiproton production obtained from the same data sample. At the energy scale of this measurement, the antihyperon contributions to antiproton production are observed to be significantly larger than predictions of commonly used hadronic production models.

The production of K_short mesons in pp collisions at a centre-of-mass energy of 0.9 TeV is studied with the LHCb detector at the Large Hadron Collider. The luminosity of the analysed sample is determined using a novel technique, involving measurements of the beam currents, sizes and positions, and is found to be 6.8 +/- 1.0 microbarn^-1. The differential prompt K_short production cross-section is measured as a function of the K_short transverse momentum and rapidity in the region 0 < pT < 1.6 GeV/c and 2.5 < y < 4.0. The data are found to be in reasonable agreement with previous measurements and generator expectations.

The production of Upsilon(1S), Upsilon(2S) and Upsilon(3S) mesons in proton-proton collisions at the centre-of-mass energy of sqrt(s)=7 TeV is studied with the LHCb detector. The analysis is based on a data sample of 25 pb-1 collected at the Large Hadron Collider. The Upsilon mesons are reconstructed in the decay mode Upsilon -> mu+ mu- and the signal yields are extracted from a fit to the mu+ mu- invariant mass distributions. The differential production cross-sections times dimuon branching fractions are measured as a function of the Upsilon transverse momentum pT and rapidity y, over the range pT < 15 GeV/c and 2.0 < y < 4.5. The cross-sections times branching fractions, integrated over these kinematic ranges, are measured to be sigma(pp -> Upsilon(1S) X) x B(Upsilon(1S)->mu+ mu-) = 2.29 {\pm} 0.01 {\pm} 0.10 -0.37 +0.19 nb, sigma(pp -> Upsilon(2S) X) x B(Upsilon(2S)->mu+ mu-) = 0.562 {\pm} 0.007 {\pm} 0.023 -0.092 +0.048 nb, sigma(pp -> Upsilon(3S) X) x B(Upsilon(3S)->mu+ mu-) = 0.283 {\pm} 0.005 {\pm} 0.012 -0.048 +0.025 nb, where the first uncertainty is statistical, the second systematic and the third is due to the unknown polarisation of the three Upsilon states.

The production of $\Upsilon (nS)$ mesons ($n=1,2,3$) in $p$Pb and Pb$p$ collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{NN}}=8.16$ TeV is measured by the LHCb experiment, using a data sample corresponding to an integrated luminosity of 31.8 nb$^{-1}$. The $\Upsilon (nS)$ mesons are reconstructed through their decays into two opposite-sign muons. The measurements comprise the differential production cross-sections of the $\Upsilon (1S)$ and $\Upsilon (2S)$ states, their forward-to-backward ratios and nuclear modification factors, performed as a function of the transverse momentum $p_{\mathrm{T}}$ and rapidity in the nucleon-nucleon centre-of-mass frame $y^*$ of the $\Upsilon (nS)$ states, in the kinematic range $p_{\rm{T}}<25$ GeV/$c$ and $1.5<y^*<4.0$ ($-5.0<y^*<-2.5$) for $p$Pb (Pb$p$) collisions. In addition, production cross-sections for $\Upsilon (3S)$ are measured integrated over phase space and the production ratios between all three $\Upsilon (nS)$ states are determined. The measurements are compared to theoretical predictions and suppressions for quarkonium in $p$Pb collisions are observed.

The production of J/psi and Upsilon mesons in pp collisions at sqrt(s) = 8 TeV is studied with the LHCb detector. The J/psi and Upsilon mesons are reconstructed in the mu+mu- decay mode and the signal yields are determined with a fit to the mu+mu- invariant mass distributions. The analysis is performed in the rapidity range 2.0<y<4.5 and transverse momentum range 0<p_T<14(15) GeV/c of the J/psi(Upsilon) mesons. The J/psi and Upsilon production cross-sections and the fraction of J/psi mesons from b-hadron decays are measured as a function of the meson p_T and y.

The production cross-sections of $J/\psi$ mesons in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=5$ TeV are measured using a data sample corresponding to an integrated luminosity of $9.13\pm0.18~\text{pb}^{-1}$, collected by the LHCb experiment. The cross-sections are measured differentially as a function of transverse momentum, $p_{\text{T}}$, and rapidity, $y$, and separately for $J/\psi$ mesons produced promptly and from beauty hadron decays (nonprompt). With the assumption of unpolarised $J/\psi$ mesons, the production cross-sections integrated over the kinematic range $0<p_{\text{T}}<20~\text{GeV}/c$ and $2.0<y<4.5$ are $8.154\pm0.010\pm0.283~\mu\text{b}$ for prompt $J/\psi$ mesons and $0.820\pm0.003\pm0.034~\mu\text{b}$ for nonprompt $J/\psi$ mesons, where the first uncertainties are statistical and the second systematic. These cross-sections are compared with those at $\sqrt{s}=8$ TeV and $13$ TeV, and are used to update the measurement of the nuclear modification factor in proton-lead collisions for $J/\psi$ mesons at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\text{NN}}}=5$ TeV. The results are compared with theoretical predictions.

The cross-section for prompt antiproton production in collisions of protons with an energy of $6.5$ TeV incident on helium nuclei at rest is measured with the LHCb experiment from a data set corresponding to an integrated luminosity of $0.5\,nb^{-1}$. The target is provided by injecting helium gas into the LHC beam line at the LHCb interaction point. The reported results, covering antiproton momenta between $12$ and $110\,\mathrm{GeV/}c$, represent the first direct determination of the antiproton production cross-section in ${\rm p He}$ collisions, and impact the interpretation of recent results on antiproton cosmic rays from space-borne experiments.

The production cross-sections of B mesons are measured in pp collisions at a centre-of-mass energy of 7 TeV, using data collected with the LHCb detector corresponding to a integrated luminosity of 0.36 fb-1. The B+, B0 and Bs0 mesons are reconstructed in the exclusive decays B+ -> J/psi K+, B0 -> J/psi K*0 and Bs0 -> J/psi phi, with J/psi -> mu+ mu-, K*0 -> K+ pi- and phi -> K+ K-. The differential cross-sections are measured as functions of B meson transverse momentum pT and rapidity y, in the range 0 < pT < 40 GeV/c and 2.0 < y < 4.5. The integrated cross-sections in the same pT and y ranges, including charge-conjugate states, are measured to be sigma(pp -> B+ + X) = 38.9 +- 0.3 (stat.) +- 2.5 (syst.) +- 1.3 (norm.) mub, sigma(pp -> B0 + X) = 38.1 +- 0.6 (stat.) +- 3.7 (syst.) +- 4.7 (norm.) mub, sigma(pp -> Bs0 + X) = 10.5 +- 0.2 (stat.) +- 0.8 (syst.) +- 1.0 (norm.) mub, where the third uncertainty arises from the pre-existing branching fraction measurements.

Production cross-sections of prompt charm mesons are measured with the first data from $pp$ collisions at the LHC at a centre-of-mass energy of $13\,\mathrm{TeV}$. The data sample corresponds to an integrated luminosity of $4.98 \pm 0.19\,\mathrm{pb}^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^{0}$, $D^{+}$, $D_{s}^{+}$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\mathrm{T}}$, and rapidity, $y$, and cover the range $0 < p_{\mathrm{T}} < 15\,\mathrm{GeV}/c$ and $2.0 < y < 4.5$. The inclusive cross-sections for the four mesons, including charge conjugation, within the range of $1 < p_{\mathrm{T}} < 8\,\mathrm{GeV}/c$ are found to be \begin{equation} \sigma(pp \to D^{0} X) = 2072 \pm 2 \pm 124\,\mu\mathrm{b}\\ \sigma(pp \to D^{+} X) = 834 \pm 2 \pm \phantom{1}78\,\mu\mathrm{b}\\ \sigma(pp \to D_{s}^{+} X) = 353 \pm 9 \pm \phantom{1}76\,\mu\mathrm{b}\\ \sigma(pp \to D^{*+} X) = 784 \pm 4 \pm \phantom{1}87\,\mu\mathrm{b} \end{equation} where the uncertainties are due to statistical and systematic uncertainties, respectively.

A precision measurement of the $Z$ boson production cross-section at $\sqrt{s} = 13$ TeV in the forward region is presented, using $pp$ collision data collected by the LHCb detector, corresponding to an integrated luminosity of 5.1 fb$^{-1}$. The production cross-section is measured using $Z\rightarrow\mu^+\mu^-$ events within the fiducial region defined as pseudorapidity $2.0<\eta<4.5$ and transverse momentum $p_{T}>20$ GeV/$c$ for both muons and dimuon invariant mass $60<M_{\mu\mu}<120$ GeV/$c^2$. The integrated cross-section is determined to be $\sigma (Z \rightarrow \mu^+ \mu^-)$ = 196.4 $\pm$ 0.2 $\pm$ 1.6 $\pm$ 3.9~pb, where the first uncertainty is statistical, the second is systematic, and the third is due to the luminosity determination. The measured results are in agreement with theoretical predictions within uncertainties.