We present a measurement of the cross section for the reaction e + e − → e + e − π + π − π + π − at SPEAR. This channel is found to be large and dominated by the process γγ → ϱ 0 ϱ 0 → π + π − π + π − . The cross section, which is small just above the four-pion threshold, exhibits a large enhancement near the ϱ 0 ϱ 0 threshold.