This paper presents measurements of charged-hadron spectra obtained in $pp$, $p$+Pb, and Pb+Pb collisions at $\sqrt{s}$ or $\sqrt{s_{_\text{NN}}}=5.02$ TeV, and in Xe+Xe collisions at $\sqrt{s_{_\text{NN}}}=5.44$ TeV. The data recorded by the ATLAS detector at the LHC have total integrated luminosities of 25 pb${}^{-1}$, 28 nb${}^{-1}$, 0.50 nb${}^{-1}$, and 3 $\mu$b${}^{-1}$, respectively. The nuclear modification factors $R_{p\text{Pb}}$ and $R_\text{AA}$ are obtained by comparing the spectra in heavy-ion and $pp$ collisions in a wide range of charged-particle transverse momenta and pseudorapidity. The nuclear modification factor $R_{p\text{Pb}}$ shows a moderate enhancement above unity with a maximum at $p_{\mathrm{T}} \approx 3$ GeV; the enhancement is stronger in the Pb-going direction. The nuclear modification factors in both Pb+Pb and Xe+Xe collisions feature a significant, centrality-dependent suppression. They show a similar distinct $p_{\mathrm{T}}$-dependence with a local maximum at $p_{\mathrm{T}} \approx 2$ GeV and a local minimum at $p_{\mathrm{T}} \approx 7$ GeV. This dependence is more distinguishable in more central collisions. No significant $|\eta|$-dependence is found. A comprehensive comparison with several theoretical predictions is also provided. They typically describe $R_\text{AA}$ better in central collisions and in the $p_{\mathrm{T}}$ range from about 10 to 100 GeV.

A measurement of $J/\psi$ and $\psi(2\mathrm{S})$ production is presented. It is based on a data sample from Pb+Pb collisions at $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV and $pp$ collisions at $\sqrt{s}$ = 5.02 TeV recorded by the ATLAS detector at the LHC in 2015, corresponding to an integrated luminosity of $0.42\mathrm{nb}^{-1}$ and $25\mathrm{pb}^{-1}$ in Pb+Pb and $pp$, respectively. The measurements of per-event yields, nuclear modification factors, and non-prompt fractions are performed in the dimuon decay channel for $9 < p_{T}^{\mu\mu} < 40$ GeV in dimuon transverse momentum, and $-2.0 < y_{\mu\mu} < 2.0$ in rapidity. Strong suppression is found in Pb+Pb collisions for both prompt and non-prompt $J/\psi$, as well as for prompt and non-prompt $\psi(2\mathrm{S})$, increasing with event centrality. The suppression of prompt $\psi(2\mathrm{S})$ is observed to be stronger than that of $J/\psi$, while the suppression of non-prompt $\psi(2\mathrm{S})$ is equal to that of the non-prompt $J/\psi$ within uncertainties, consistent with the expectation that both arise from \textit{b}-quarks propagating through the medium. Despite prompt and non-prompt $J/\psi$ arising from different mechanisms, the dependence of their nuclear modification factors on centrality is found to be quite similar.

Heavy-flavour hadron production provides information about the transport properties and microscopic structure of the quark-gluon plasma created in ultra-relativistic heavy-ion collisions. A measurement of the muons from semileptonic decays of charm and bottom hadrons produced in Pb+Pb and $pp$ collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV with the ATLAS detector at the Large Hadron Collider is presented. The Pb+Pb data were collected in 2015 and 2018 with sampled integrated luminosities of $208~\mathrm{\mu b}^{-1}$ and $38~\mathrm{\mu b^{-1}}$, respectively, and $pp$ data with a sampled integrated luminosity of $1.17~\mathrm{pb}^{-1}$ were collected in 2017. Muons from heavy-flavour semileptonic decays are separated from the light-flavour hadronic background using the momentum imbalance between the inner detector and muon spectrometer measurements, and muons originating from charm and bottom decays are further separated via the muon track's transverse impact parameter. Differential yields in Pb+Pb collisions and differential cross sections in $pp$ collisions for such muons are measured as a function of muon transverse momentum from 4 GeV to 30 GeV in the absolute pseudorapidity interval $|\eta| < 2$. Nuclear modification factors for charm and bottom muons are presented as a function of muon transverse momentum in intervals of Pb+Pb collision centrality. The measured nuclear modification factors quantify a significant suppression of the yields of muons from decays of charm and bottom hadrons, with stronger effects for muons from charm hadron decays.

The transverse momentum ($p_{\rm T}$) and centrality dependence of the nuclear modification factor $R_{\rm AA}$ of prompt and non-prompt J$/\psi$, the latter originating from the weak decays of beauty hadrons, have been measured by the ALICE collaboration in Pb$-$Pb collisions at $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV. The measurements are carried out through the ${\rm e}^{+}{\rm e}^{-}$ decay channel at midrapidity ($|y| < 0.9$) in the transverse momentum region $1.5 < p_{\rm T} < 10$ GeV/$c$. Both prompt and non-prompt J$/\psi$ measurements indicate a significant suppression for $p_{\rm T} >$ 5 GeV/$c$, which becomes stronger with increasing collision centrality. The results are consistent with similar LHC measurements in the overlapping $p_{\rm T}$ intervals, and cover the kinematic region down to $p_{\rm T}$ = 1.5 GeV/$c$ at midrapidity, not accessible by other LHC experiments. The suppression of prompt J$/\psi$ in central and semicentral collisions exhibits a decreasing trend towards lower transverse momentum, described within uncertainties by models implementing J$/\psi$ production from recombination of c and $\overline{\rm c}$ quarks produced independently in different partonic scatterings. At high transverse momentum, transport models including quarkonium dissociation are able to describe the suppression for prompt J$/\psi$. For non-prompt J$/\psi$, the suppression predicted by models including both collisional and radiative processes for the computation of the beauty-quark energy loss inside the quark$-$gluon plasma is consistent with measurements within uncertainties.

The transverse momentum spectra of charged particles have been measured in pp and PbPb collisions at sqrt(sNN) = 2.76 TeV by the CMS experiment at the LHC. In the transverse momentum range pt = 5-10 GeV/c, the charged particle yield in the most central PbPb collisions is suppressed by up to a factor of 5 compared to the pp yield scaled by the number of incoherent nucleon-nucleon collisions. At higher pt, this suppression is significantly reduced, approaching roughly a factor of 2 for particles with pt in the range pt=40-100 GeV/c.

Parton energy loss in the quark-gluon plasma (QGP) is studied with a measurement of photon-tagged jet production in 1.7 nb$^{-1}$ of Pb+Pb data and 260 pb$^{-1}$ of $pp$ data, both at $\sqrt{s_\mathrm{NN}} = 5.02$ TeV, with the ATLAS detector. The process $pp \to \gamma$+jet+$X$ and its analogue in Pb+Pb collisions is measured in events containing an isolated photon with transverse momentum ($p_\mathrm{T}$) above $50$ GeV and reported as a function of jet $p_\mathrm{T}$. This selection results in a sample of jets with a steeply falling $p_\mathrm{T}$ distribution that are mostly initiated by the showering of quarks. The $pp$ and Pb+Pb measurements are used to report the nuclear modification factor, $R_\mathrm{AA}$, and the fractional energy loss, $S_\mathrm{loss}$, for photon-tagged jets. In addition, the results are compared with the analogous ones for inclusive jets, which have a significantly smaller quark-initiated fraction. The $R_\mathrm{AA}$ and $S_\mathrm{loss}$ values are found to be significantly different between those for photon-tagged jets and inclusive jets, demonstrating that energy loss in the QGP is sensitive to the colour-charge of the initiating parton. The results are also compared with a variety of theoretical models of colour-charge-dependent energy loss.

Isolated photon production is measured in proton-proton and lead-lead collisions at nucleon-nucleon centre-of-mass energies of 2.76 TeV in the pseudorapidity range |eta|<1.44 and transverse energies ET between 20 and 80 GeV with the CMS detector at the LHC. The measured ET spectra are found to be in good agreement with next-to-leading-order perturbative QCD predictions. The ratio of PbPb to pp isolated photon ET-differential yields, scaled by the number of incoherent nucleon-nucleon collisions, is consistent with unity for all PbPb reaction centralities.

The first measurements of the production of muons and electrons from heavy-flavour hadron decays in Xe-Xe collisions at $\sqrt{s_{\rm NN}}$ = 5.44 TeV, using the ALICE detector at the LHC, are reported. The measurement of the nuclear modification factor $R_{\rm AA}$ is performed as a function of transverse momentum $p_{\rm T}$ in several centrality classes at forward rapidity ($2.5 < y <4$) and midrapidity ($\vert y \vert < 0.8$) for muons and electrons from heavy-flavour hadron decays, respectively. A suppression by a factor up to about 2.5 compared to the binary-scaled pp reference is observed in central collisions at both central and forward rapidities. The $R_{\rm AA}$ of muons from heavy-flavour hadron decays is compared to previous measurements in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV. When the nuclear modification factors are compared in the centrality classes 0-10% for Xe-Xe collisions and 10-20% for Pb-Pb collisions, which have similar charged-particle multiplicity density, a similar suppression, with $R_{\rm AA} \sim 0.4$ in the $p_{\rm T}$ interval $4 < p_{\rm T} < 8$ GeV/$c$, is observed. The comparison of the measured $R_{\rm AA}$ values in the two collision systems brings new insights on the properties of the quark-gluon plasma by investigating the system-size and path-length dependence of medium-induced parton energy loss. The results of muons and electrons from heavy-flavour hadron decays provide new constraints to model calculations.

The cross sections for $\Upsilon$(1S), $\Upsilon$(2S), and $\Upsilon$(3S) production in lead-lead (PbPb) and proton-proton (pp) collisions at $\sqrt{s_{_\mathrm{NN}}} =$ 5.02 TeV have been measured using the CMS detector at the LHC. The nuclear modification factors, R$_\mathrm{AA}$, derived from the PbPb-to-pp ratio of yields for each state, are studied as functions of meson rapidity and transverse momentum, as well as PbPb collision centrality. The yields of all three states are found to be significantly suppressed, and compatible with a sequential ordering of the suppression, R$_\mathrm{AA}$($\Upsilon$(1S)) $>$ R$_\mathrm{AA}$($\Upsilon$(2S)) $>$ R$_\mathrm{AA}$($\Upsilon$(3S)) . The suppression of $\Upsilon$(1S) is larger than that seen at $\sqrt{s_{_\mathrm{NN}}} =$ 2.76 TeV, although the two are compatible within uncertainties. The upper limit on the R$_\mathrm{AA}$ of $\Upsilon$(3S) integrated over $p_\mathrm{T}$ and rapidity is 0.094 at 95% confidence level, which is the strongest suppression observed for any hadron species in heavy ion collisions to date.

The production of the $\psi(2S)$ charmonium state was measured with ALICE in Pb-Pb collisions at $\sqrt{s_{\rm NN}}=5.02$ TeV, in the dimuon decay channel. A significant signal was observed for the first time at LHC energies down to zero transverse momentum, at forward rapidity ($2.5<y<4$). The measurement of the ratio of the inclusive production cross sections of the $\psi(2S)$ and J/$\psi$ resonances is reported as a function of the centrality of the collisions and of transverse momentum, in the region $p_{\rm T}<12$ GeV/$c$. The results are compared with the corresponding measurements in pp collisions, by forming the double ratio $[\sigma^{\psi(2S)}/\sigma^{J/\psi}]_{\rm{Pb-Pb}}/[\sigma^{\psi(2S)}/\sigma^{J/\psi}]_{\rm{pp}}$. It is found that in Pb-Pb collisions the $\psi(2S)$ is suppressed by a factor of $\sim 2$ with respect to the J/$\psi$. The $\psi(2S)$ nuclear modification factor $R_{\rm AA}$ was also obtained as a function of both centrality and $p_{\rm T}$. The results show that the $\psi(2S)$ resonance yield is strongly suppressed in Pb-Pb collisions, by a factor up to $\sim 3$ with respect to pp. Comparisons of cross section ratios with previous SPS findings by the NA50 experiment and of $R_{\rm AA}$ with higher-$p_{\rm T}$ results at LHC energy are also reported. These results and the corresponding comparisons with calculations of transport and statistical models address questions on the presence and properties of charmonium states in the quark-gluon plasma formed in nuclear collisions at the LHC.