The energy dependence of the cross section for neutrino- and antineutrino-nucleon charged-current interactions has been determined from data taken in Fermilab's dichromatic neutrino beam. σνE=(0.669±0.003±0.024)×10−38 cm2/GeV and σν¯E=(0.340±0.003±0.02)×10−38 cm2/GeV are found. These results are higher than some previous measurements.