The observation of the production of four top quarks in proton-proton collisions is reported, based on a data sample collected by the CMS experiment at a center-of-mass energy of 13 TeV in 2016-2018 at the CERN LHC and corresponding to an integrated luminosity of 138 fb$^{-1}$. Events with two same-sign, three, or four charged leptons (electrons and muons) and additional jets are analyzed. Compared to previous results in these channels, updated identification techniques for charged leptons and jets originating from the hadronization of b quarks, as well as a revised multivariate analysis strategy to distinguish the signal process from the main backgrounds, lead to an improved expected signal significance of 4.9 standard deviations above the background-only hypothesis. Four top quark production is observed with a significance of 5.6 standard deviations, and its cross section is measured to be 17.7 $^{+3.7}_{-3.5}$ (stat) $^{+2.3}_{-1.9}$ (syst) fb, in agreement with the available standard model predictions.

Differential cross sections for the Drell-Yan process, including Z boson production, using the dimuon decay channel are measured in proton-lead (pPb) collisions at a nucleon-nucleon centre-of-mass energy of 8.16 TeV. A data sample recorded with the CMS detector at the LHC is used, corresponding to an integrated luminosity of 173 nb$^{-1}$. The differential cross section as a function of the dimuon mass is measured in the range 15-600 GeV, for the first time in proton-nucleus collisions. It is also reported as a function of dimuon rapidity over the mass ranges 15-60 GeV and 60-120 GeV, and ratios for the p-going over the Pb-going beam directions are built. In both mass ranges, the differential cross sections as functions of the dimuon transverse momentum $p_\mathrm{T}$ and of a geometric variable $\phi^*$ are measured, where $\phi^*$ highly correlates with $p_\mathrm{T}$ but is determined with higher precision. In the Z mass region, the rapidity dependence of the data indicate a modification of the distribution of partons within a lead nucleus as compared to the proton case. The data are more precise than predictions based upon current models of parton distributions.

Three of the most significant measured deviations from standard model predictions, the enhanced decay rate for B $\to$ D$^{(*)}\tau\nu$, hints of lepton universality violation in B $\to$ K$^{(*)}\ell\ell$ decays, and the anomalous magnetic moment of the muon, can be explained by the existence of leptoquarks (LQs) with large couplings to third-generation quarks and masses at the TeV scale. The existence of these states can be probed at the LHC in high energy proton-proton collisions. A novel search is presented for pair production of LQs coupled to a top quark and a muon using data at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb$^{-1}$, recorded by the CMS experiment. No deviation from the standard model prediction has been observed and scalar LQs decaying exclusively into t$\mu$ are excluded up to masses of 1420 GeV. The results of this search are combined with those from previous searches for LQ decays into t$\tau$ and b$\nu$, which excluded scalar LQs below masses of 900 and 1080 GeV. Vector LQs are excluded up to masses of 1190 GeV for all possible combinations of branching fractions to t$\mu$, t$\tau$ and b$\nu$. With this analysis, all relevant couplings of LQs with an electric charge of -1/3 to third-generation quarks are probed for the first time.

A measurement of the cross section of the associated production of a single top quark and a W boson in final states with a muon or electron and jets in proton-proton collisions at $\sqrt{s}$ = 13 TeV is presented. The data correspond to an integrated luminosity of 36 fb$^{-1}$ collected with the CMS detector at the CERN LHC in 2016. A boosted decision tree is used to separate the tW signal from the dominant $\mathrm{t\bar{t}}$ background, whilst the subleading W+jets and multijet backgrounds are constrained using data-based estimates. This result is the first observation of the tW process in final states containing a muon or electron and jets, with a significance exceeding 5 standard deviations. The cross section is determined to be 89 $\pm$ 4 (stat) $\pm$ 12 (syst) pb, consistent with the standard model.

The differential cross sections for inclusive production of B+ hadrons are measured as a function of the B+ transverse momentum pT[B] and rapidity y[B] in pp collisions at a centre-of-mass energy of 13 TeV, using data collected by the CMS experiment that correspond to an integrated luminosity of 49.4 inverse picobarns. The measurement uses the exclusive decay channel B+ to J/psi K+, with J/psi mesons that decay to a pair of muons. The results show a reasonable agreement with theoretical calculations within the uncertainties.

A search for physics beyond the standard model in events with at least three charged leptons (electrons or muons) is presented. The data sample corresponds to an integrated luminosity of 137 fb$^{-1}$ of proton-proton collisions at $\sqrt{s} =$ 13 TeV, collected with the CMS detector at the LHC in 2016-2018. The two targeted signal processes are pair production of type-III seesaw heavy fermions and production of a light scalar or pseudoscalar boson in association with a pair of top quarks. The heavy fermions may be manifested as an excess of events with large values of leptonic transverse momenta or missing transverse momentum. The light scalars or pseudoscalars may create a localized excess in the dilepton mass spectra. The results exclude heavy fermions of the type-III seesaw model for masses below 880 GeV at 95% confidence level in the scenario of equal branching fractions to each lepton flavor. This is the most restrictive limit on the flavor-democratic scenario of the type-III seesaw model to date. Assuming a Yukawa coupling of unit strength to top quarks, branching fractions of new scalar (pseudoscalar) bosons to dielectrons or dimuons above 0.004 (0.03) and 0.04 (0.03) are excluded at 95% confidence level for masses in the range 15-75 and 108-340 GeV, respectively. These are the first limits in these channels on an extension of the standard model with scalar or pseudoscalar particles.

The cross section of top quark-antiquark pair production in proton-proton collisions at sqrt(s) = 13 TeV is measured by the CMS experiment at the LHC, using data corresponding to an integrated luminosity of 2.2 inverse femtobarns. The measurement is performed by analyzing events in which the final state includes one electron, one muon, and two or more jets, at least one of which is identified as originating from hadronization of a b quark. The measured cross section is 815 +/- 9 (stat) +/- 38 (syst) +/- 19 (lumi) pb, in agreement with the expectation from the standard model.

Differential cross sections for a W boson produced in association with jets are measured in a data sample of proton-proton collisions at a center-of-mass energy of 8 TeV recorded with the CMS detector and corresponding to an integrated luminosity of 19.6 inverse femtobarns. The W bosons are identified through their decay mode W to mu nu. The cross sections are reported as functions of jet multiplicity, transverse momenta, and the scalar sum of jet transverse momenta (HT) for different jet multiplicities. Distributions of the angular correlations between the jets and the muon are examined, as well as the average number of jets as a function of HT and as a function of angular variables. The measured differential cross sections are compared with tree-level and higher-order recent event generators, as well as next-to-leading-order and next-to-next-to-leading-order theoretical predictions. The agreement of the generators with the measurements builds confidence in their use for the simulation of W+jets background processes in searches for new physics at the LHC.

A search for Higgs bosons that decay into a bottom quark-antiquark pair and are accompanied by at least one additional bottom quark is performed with the CMS detector. The data analyzed were recorded in proton-proton collisions at a centre-of-mass energy of $\sqrt{s} =$ 13 TeV at the LHC, corresponding to an integrated luminosity of 35.7 fb$^{-1}$. The final state considered in this analysis is particularly sensitive to signatures of a Higgs sector beyond the standard model, as predicted in the generic class of two Higgs doublet models (2HDMs). No signal above the standard model background expectation is observed. Stringent upper limits on the cross section times branching fraction are set for Higgs bosons with masses up to 1300 GeV. The results are interpreted within several MSSM and 2HDM scenarios.

A measurement of the differential cross sections for a W boson produced in association with jets in the muon decay channel is presented. The measurement is based on 13 TeV proton-proton collision data corresponding to an integrated luminosity of 2.2 inverse femtobarns, recorded by the CMS detector at the LHC. The cross sections are reported as functions of jet multiplicity, jet transverse momentum pT, jet rapidity, the scalar pT sum of the jets, and angular correlations between the muon and the jet for different jet multiplicities. The measured cross sections are in agreement with predictions that include multileg leading-order (LO) and next-to-LO matrix element calculations interfaced with parton showers, as well as a next-to-next-to-LO calculation for the W boson and one jet production.