Ultrarelativistic heavy ion collisions recreate in the laboratory the thermodynamical conditions prevailing in the early universe up to 10$^{-6}$ seconds, thereby allowing the study of the quark-gluon plasma (QGP), a state of quantum chromodynamics (QCD) matter with deconfined partons. The top quark, the heaviest elementary particle known, is accessible in nucleus-nucleus collisions at the CERN LHC, and constitutes a novel probe of the QGP. Here, we report the first-ever evidence for the production of top quarks in nucleus-nucleus collisions, using lead-lead collision data at a nucleon-nucleon centre-of-mass energy of 5.02 TeV recorded by the CMS experiment. Two methods are used to measure the cross section for top quark pair production ($\sigma_\mathrm{t\bar{t}}$) via the decay into charged leptons (electrons or muons) and bottom quarks. One method relies on the leptonic information alone, and the second one exploits, in addition, the presence of bottom quarks. The measured cross sections, $\sigma_\mathrm{t\bar{t}} = $ 2.54 $^{+0.84}_{-0.74}$ and 2.03 $^{+0.71}_{-0.64}$ $\mu$b, respectively, are compatible with expectations from scaled proton-proton data and QCD predictions.

The Upsilon production cross section in proton-proton collisions at sqrt(s) = 7 TeV is measured using a data sample collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 3.1 +/- 0.3 inverse picobarns. Integrated over the rapidity range |y|<2, we find the product of the Upsilon(1S) production cross section and branching fraction to dimuons to be sigma(pp to Upsilon(1S) X) B(Upsilon(1S) to mu+ mu-) = 7.37 +/- 0.13^{+0.61}_{-0.42}\pm 0.81 nb, where the first uncertainty is statistical, the second is systematic, and the third is associated with the estimation of the integrated luminosity of the data sample. This cross section is obtained assuming unpolarized Upsilon(1S) production. If the Upsilon(1S) production polarization is fully transverse or fully longitudinal the cross section changes by about 20%. We also report the measurement of the Upsilon(1S), Upsilon(2S), and Upsilon(3S) differential cross sections as a function of transverse momentum and rapidity.

The inclusive b-jet production cross section in pp collisions at a center-of-mass energy of 7 TeV is measured using data collected by the CMS experiment at the LHC. The cross section is presented as a function of the jet transverse momentum in the range 18 < pT < 200 GeV for several rapidity intervals. The results are also given as the ratio of the b-jet production cross section to the inclusive jet production cross section. The measurement is performed with two different analyses, which differ in their trigger selection and b-jet identification: a jet analysis that selects events with a b jet using a sample corresponding to an integrated luminosity of 34 inverse picobarns, and a muon analysis requiring a b jet with a muon based on an integrated luminosity of 3 inverse picobarns. In both approaches the b jets are identified by requiring a secondary vertex. The results from the two methods are in agreement with each other and with next-to-leading order calculations, as well as with predictions based on the PYTHIA event generator.

Searches for anomalous top quark-antiquark production are presented, based on pp collisions at sqrt(s) = 8 TeV. The data, corresponding to an integrated luminosity of 19.7 inverse femtobarns, were collected with the CMS detector at the LHC. The observed ttbar invariant mass spectrum is found to be compatible with the standard model prediction. Limits on the production cross section times branching fraction probe, for the first time, a region of parameter space for certain models of new physics not yet constrained by precision measurements.

Measurements of the differential cross sections for the production of exactly four jets in proton-proton collisions are presented as a function of the transverse momentum pt and pseudorapidity eta, together with the correlations in azimuthal angle and the pt balance among the jets. The data sample was collected in 2010 at a center-of-mass energy of 7 TeV with the CMS detector at the LHC, with an integrated luminosity of 36 inverse picobarns. The cross section for a final state with a pair of hard jets with pt > 50 GeV and another pair with pt > 20 GeV within abs(eta) < 4.7 is measured to be sigma = 330 +- 5 (stat.) +- 45 (syst.) nb. It is found that fixed-order matrix element calculations including parton showers describe the measured differential cross sections in some regions of phase space only, and that adding contributions from double parton scattering brings the Monte Carlo predictions closer to the data.

Measurements are presented of the associated production of a W boson and a charm-quark jet (W + c) in pp collisions at a center-of-mass energy of 7 TeV. The analysis is conducted with a data sample corresponding to a total integrated luminosity of 5 inverse femtobarns, collected by the CMS detector at the LHC. W boson candidates are identified by their decay into a charged lepton (muon or electron) and a neutrino. The W + c measurements are performed for charm-quark jets in the kinematic region $p_T^{jet} \gt$ 25 GeV, $|\eta^{jet}| \lt$ 2.5, for two different thresholds for the transverse momentum of the lepton from the W-boson decay, and in the pseudorapidity range $|\eta^{\ell}| \lt$ 2.1. Hadronic and inclusive semileptonic decays of charm hadrons are used to measure the following total cross sections: $\sigma(pp \to W + c + X) \times B(W \to \ell \nu)$ = 107.7 +/- 3.3 (stat.) +/- 6.9 (syst.) pb ($p_T^{\ell} \gt$ 25 GeV) and $\sigma(pp \to W + c + X) \times B(W \to \ell \nu)$ = 84.1 +/- 2.0 (stat.) +/- 4.9 (syst.) pb ($p_T^{\ell} \gt$ 35 GeV), and the cross section ratios $\sigma(pp \to W^+ + \bar{c} + X)/\sigma(pp \to W^- + c + X)$ = 0.954 +/- 0.025 (stat.) +/- 0.004 (syst.) ($p_T^{\ell} \gt$ 25 GeV) and $\sigma(pp \to W^+ + \bar{c} + X)\sigma(pp \to W^- + c + X)$ = 0.938 +/- 0.019 (stat.) +/- 0.006 (syst.) ($p_T^{\ell} \gt$ 35 GeV). Cross sections and cross section ratios are also measured differentially with respect to the absolute value of the pseudorapidity of the lepton from the W-boson decay. These are the first measurements from the LHC directly sensitive to the strange quark and antiquark content of the proton. Results are compared with theoretical predictions and are consistent with the predictions based on global fits of parton distribution functions.

A measurement of the b-hadron production cross section in proton-proton collisions at sqrt(s)=7 TeV is presented. The dataset, corresponding to 85 inverse nanobarns, was recorded with the CMS experiment at the LHC using a low-threshold single-muon trigger. Events are selected by the presence of a muon with transverse momentum greater than 6 GeV with respect to the beam direction and pseudorapidity less than 2.1. The transverse momentum of the muon with respect to the closest jet discriminates events containing b hadrons from background. The inclusive b-hadron production cross section is presented as a function of muon transverse momentum and pseudorapidity. The measured total cross section in the kinematic acceptance is sigma(pp to b+X to mu + X') =1.32 +/- 0.01 (stat) +/- 0.30 (syst) +/- 0.15 (lumi) microbarns.

The observation of the production of four top quarks in proton-proton collisions is reported, based on a data sample collected by the CMS experiment at a center-of-mass energy of 13 TeV in 2016-2018 at the CERN LHC and corresponding to an integrated luminosity of 138 fb$^{-1}$. Events with two same-sign, three, or four charged leptons (electrons and muons) and additional jets are analyzed. Compared to previous results in these channels, updated identification techniques for charged leptons and jets originating from the hadronization of b quarks, as well as a revised multivariate analysis strategy to distinguish the signal process from the main backgrounds, lead to an improved expected signal significance of 4.9 standard deviations above the background-only hypothesis. Four top quark production is observed with a significance of 5.6 standard deviations, and its cross section is measured to be 17.7 $^{+3.7}_{-3.5}$ (stat) $^{+2.3}_{-1.9}$ (syst) fb, in agreement with the available standard model predictions.

A measurement of the exclusive two-photon production of muon pairs in proton-proton collisions at sqrt(s)= 7 TeV, pp to p mu^+ mu^- p, is reported using data corresponding to an integrated luminosity of 40 inverse picobarns. For muon pairs with invariant mass greater than 11.5 GeV, transverse momentum pT(mu) > 4 GeV and pseudorapidity |eta(mu)| < 2.1, a fit to the dimuon pt(mu^+ mu^-) distribution results in a measured cross section of sigma(pp to p mu^+ mu^- p) = 3.38 [+0.58 -0.55] (stat.) +/- 0.16 (syst.) +/- 0.14 (lumi.) pb, consistent with the theoretical prediction evaluated with the event generator Lpair. The ratio to the predicted cross section is 0.83 [+0.14-0.13] (stat.) +/- 0.04 (syst.) +/- 0.03 (lumi.). The characteristic distributions of the muon pairs produced via photon-photon fusion, such as the muon acoplanarity, the muon pair invariant mass and transverse momentum agree with those from the theory.

A measurement of the W$^+$W$^-$ boson pair production cross section in proton-proton collisions at $\sqrt{s} =$ 13 TeV is presented. The data used in this study are collected with the CMS detector at the CERN LHC and correspond to an integrated luminosity of 35.9 fb$^{-1}$. The W$^+$W$^-$ candidate events are selected by requiring two oppositely charged leptons (electrons or muons). Two methods for reducing background contributions are employed. In the first one, a sequence of requirements on kinematic quantities is applied allowing a measurement of the total production cross section: 117.6 $\pm$ 6.8 pb, which agrees well with the theoretical prediction. Fiducial cross sections are also reported for events with zero or one jet, and the change in the zero-jet fiducial cross section with the jet transverse momentum threshold is measured. Normalized differential cross sections are reported within the fiducial region. A second method for suppressing background contributions employs two random forest classifiers. The analysis based on this method includes a measurement of the total production cross section and also a measurement of the normalized jet multiplicity distribution in W$^+$W$^-$ events. Finally, a dilepton invariant mass distribution is used to probe for physics beyond the standard model in the context of an effective field theory, and constraints on the presence of dimension-6 operators are derived.