The contributions of the PLUTO experiment to e + e − physics at collision energies in the range of 3–32 GeV are reviewed. The review briefly sketches the storage rings DORIS and PETRA at DESY, and describes the most important features of the PLUTO detector, of data processing, and of the analysis methods. It covers the physics results in the fields of electroweak interactions, of the heavy lepton τ and the search for still heavier leptons, of hadron production with evidence for quark and gluon jets, as well as for single and multiple gluon emission, of Y decays and their relation to QCD, and presents results in high-energy photon-photon interactions, including the first measurement of the photon structure function.