This search, a type not previously performed at ATLAS, uses a comparison of the production cross sections for $e^+ \mu^-$ and $e^- \mu^+$ pairs to constrain physics processes beyond the Standard Model. It uses $139 \text{fb}^{-1}$ of proton$-$proton collision data recorded at $\sqrt{s} = 13$ TeV at the LHC. Targeting sources of new physics which prefer final states containing $e^{+}\mu^{-}$ to $e^{-}\mu^{+}$, the search contains two broad signal regions which are used to provide model-independent constraints on the ratio of cross sections at the 2% level. The search also has two special selections targeting supersymmetric models and leptoquark signatures. Observations using one of these selections are able to exclude, at 95% confidence level, singly produced smuons with masses up to 640 GeV in a model in which the only other light sparticle is a neutralino when the $R$-parity-violating coupling $\lambda'_{231}$ is close to unity. Observations using the other selection exclude scalar leptoquarks with masses below 1880 GeV when $g_{\text{1R}}^{eu}=g_{\text{1R}}^{\mu c}=1$, at 95% confidence level. The limit on the coupling reduces to $g_{\text{1R}}^{eu}=g_{\text{1R}}^{\mu c}=0.46$ for a mass of 1420 GeV.
Searches for scalar leptoquarks pair-produced in proton-proton collisions at $\sqrt{s}=13$ TeV at the Large Hadron Collider are performed by the ATLAS experiment. A data set corresponding to an integrated luminosity of 36.1 fb$^{-1}$ is used. Final states containing two electrons or two muons and two or more jets are studied, as are states with one electron or muon, missing transverse momentum and two or more jets. No statistically significant excess above the Standard Model expectation is observed. The observed and expected lower limits on the leptoquark mass at 95% confidence level extend up to 1.29 TeV and 1.23 TeV for first- and second-generation leptoquarks, respectively, as postulated in the minimal Buchm\"uller-R\"uckl-Wyler model, assuming a branching ratio into a charged lepton and a quark of 50%. In addition, measurements of particle-level fiducial and differential cross sections are presented for the $Z\rightarrow ee$, $Z\rightarrow\mu\mu$ and $t\bar{t}$ processes in several regions related to the search control regions. Predictions from a range of generators are compared with the measurements, and good agreement is seen for many of the observables. However, the predictions for the $Z\rightarrow\ell\ell$ measurements in observables sensitive to jet energies disagree with the data.
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