We present a measurement of the $\nu_e$-interaction rate in the MicroBooNE detector that addresses the observed MiniBooNE anomalous low-energy excess (LEE). The approach taken isolates neutrino interactions consistent with the kinematics of charged-current quasi-elastic (CCQE) events. The topology of such signal events has a final state with 1 electron, 1 proton, and 0 mesons ($1e1p$). Multiple novel techniques are employed to identify a $1e1p$ final state, including particle identification that use two methods of deep-learning-based image identification, and event isolation using a boosted decision-tree ensemble trained to recognize two-body scattering kinematics. This analysis selects 25 $\nu_e$-candidate events in the reconstructed neutrino energy range of 200--1200 MeV, while $29.0 \pm 1.9_\text{(sys)} \pm 5.4_\text{(stat)}$ are predicted when using $\nu_\mu$ CCQE interactions as a constraint. We use a simplified model to translate the MiniBooNE LEE observation into a prediction for a $\nu_e$ signal in MicroBooNE. A $\Delta \chi^2$ test statistic, based on the combined Neyman--Pearson $\chi^2$ formalism, is used to define frequentist confidence intervals for the LEE signal strength. Using this technique, in the case of no LEE signal, we expect this analysis to exclude a normalization factor of 0.75 (0.98) times the median MiniBooNE LEE signal strength at 90% ($2\sigma$) confidence level, while the MicroBooNE data yield an exclusion of 0.25 (0.38) times the median MiniBooNE LEE signal strength at 90% ($2\sigma$) confidence
We report a search for an anomalous excess of inclusive charged-current (CC) $\nu_e$ interactions using the Wire-Cell event reconstruction package in the MicroBooNE experiment, which is motivated by the previous observation of a low-energy excess (LEE) of electromagnetic events from the MiniBooNE experiment. With a single liquid argon time projection chamber detector, the measurements of $\nu_{\mu}$ CC interactions as well as $\pi^0$ interactions are used to constrain signal and background predictions of $\nu_e$ CC interactions. A data set collected from February 2016 to July 2018 corresponding to an exposure of 6.369 $\times$ 10$^{20}$ protons on target from the Booster Neutrino Beam at FNAL is analyzed. With $x$ representing an overall normalization factor and referred to as the LEE strength parameter, we select 56 fully contained $\nu_e$ CC candidates while expecting 69.6 $\pm$ 8.0 (stat.) $\pm$ 5.0 (sys.) and 103.8 $\pm$ 9.0 (stat.) $\pm$ 7.4 (sys.) candidates after constraints for the absence (eLEE$_{x=0}$) of the median signal strength derived from the MiniBooNE observation and the presence (eLEE$_{x=1}$) of that signal strength, respectively. Under a nested hypothesis test using both rate and shape information in all available channels, the best-fit $x$ is determined to be 0 (eLEE$_{x=0}$) with a 95.5% confidence level upper limit of $x$ at 0.502. Under a simple-vs-simple hypotheses test, the eLEE$_{x=1}$ hypothesis is rejected at 3.75$\sigma$, while the eLEE$_{x=0}$ hypothesis is shown to be consistent with the observation at 0.45$\sigma$. In the context of the eLEE model, the estimated 68.3% confidence interval of the $\nu_e$ hypothesis to explain the LEE observed in the MiniBooNE experiment is disfavored at a significance level of more than 2.6$\sigma$ (3.0$\sigma$) considering MiniBooNE's full (statistical) uncertainties.
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