The production cross-sections of $J/\psi$ mesons in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=5$ TeV are measured using a data sample corresponding to an integrated luminosity of $9.13\pm0.18~\text{pb}^{-1}$, collected by the LHCb experiment. The cross-sections are measured differentially as a function of transverse momentum, $p_{\text{T}}$, and rapidity, $y$, and separately for $J/\psi$ mesons produced promptly and from beauty hadron decays (nonprompt). With the assumption of unpolarised $J/\psi$ mesons, the production cross-sections integrated over the kinematic range $0<p_{\text{T}}<20~\text{GeV}/c$ and $2.0<y<4.5$ are $8.154\pm0.010\pm0.283~\mu\text{b}$ for prompt $J/\psi$ mesons and $0.820\pm0.003\pm0.034~\mu\text{b}$ for nonprompt $J/\psi$ mesons, where the first uncertainties are statistical and the second systematic. These cross-sections are compared with those at $\sqrt{s}=8$ TeV and $13$ TeV, and are used to update the measurement of the nuclear modification factor in proton-lead collisions for $J/\psi$ mesons at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\text{NN}}}=5$ TeV. The results are compared with theoretical predictions.

The interpretation of cosmic antiproton flux measurements from space-borne experiments is currently limited by the knowledge of the antiproton production cross-section in collisions between primary cosmic rays and the interstellar medium. Using collisions of protons with an energy of 6.5 TeV incident on helium nuclei at rest in the proximity of the interaction region of the LHCb experiment, the ratio of antiprotons originating from antihyperon decays to prompt production is measured for antiproton momenta between 12 and 110 GeV/c. The dominant antihyperon contribution, namely $\bar{\Lambda} \to \bar{p} \pi^+$ decays from promptly produced $\bar{\Lambda}$ particles, is also exclusively measured. The results complement the measurement of prompt antiproton production obtained from the same data sample. At the energy scale of this measurement, the antihyperon contributions to antiproton production are observed to be significantly larger than predictions of commonly used hadronic production models.

A precision measurement of the $Z$ boson production cross-section at $\sqrt{s} = 13$ TeV in the forward region is presented, using $pp$ collision data collected by the LHCb detector, corresponding to an integrated luminosity of 5.1 fb$^{-1}$. The production cross-section is measured using $Z\rightarrow\mu^+\mu^-$ events within the fiducial region defined as pseudorapidity $2.0<\eta<4.5$ and transverse momentum $p_{T}>20$ GeV/$c$ for both muons and dimuon invariant mass $60<M_{\mu\mu}<120$ GeV/$c^2$. The integrated cross-section is determined to be $\sigma (Z \rightarrow \mu^+ \mu^-)$ = 196.4 $\pm$ 0.2 $\pm$ 1.6 $\pm$ 3.9~pb, where the first uncertainty is statistical, the second is systematic, and the third is due to the luminosity determination. The measured results are in agreement with theoretical predictions within uncertainties.

The first measurement of the $Z$ boson production cross-section at centre-of-mass energy $\sqrt{s} = 5.02\,$TeV in the forward region is reported, using $pp$ collision data collected by the LHCb experiment in year 2017, corresponding to an integrated luminosity of $100 \pm 2\,\rm{pb^{-1}}$. The production cross-section is measured for final-state muons in the pseudorapidity range $2.0<\eta<4.5$ with transverse momentum $p_{\rm{T}}> 20\,\rm{GeV/}\it{c}$. The integrated cross-section is determined to be \[ \sigma_{Z \rightarrow \mu^{+}\mu^{-}} = 39.6 \pm 0.7\,(\rm{stat}) \pm 0.6\,(\rm{syst}) \pm 0.8\,(\rm{lumi}) \ \rm{pb} \] for the di-muon invariant mass in the range $60<M_{\mu\mu}<120\,\rm{GeV/}\it{c^{2}}$. This result and the differential cross-section results are in good agreement with theoretical predictions at next-to-next-to-leading order in the strong coupling. Based on a previous LHCb measurement of the $Z$ boson production cross-section in $p$Pb collisions at $\sqrt{s_{NN}}=5.02$ TeV, the nuclear modification factor $R_{p\rm{Pb}}$ is measured for the first time at this energy. The measured values are $1.2^{+0.5}_{-0.3}\,(\rm{stat}) \pm 0.1\,(\rm{syst})$ in the forward region ($1.53<y^*_{\mu}<4.03$) and $3.6^{+1.6}_{-0.9}\,(\rm{stat}) \pm 0.2\,(\rm{syst})$ in the backward region ($-4.97<y^*_{\mu}<-2.47$), where $y^*_{\mu}$ represents the muon rapidity in the centre-of-mass frame.

Using a data sample corresponding to an integrated luminosity of $2.0\,fb^{-1}$, collected by the LHCb experiment, the production of the $\eta_c(1S)$ state in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=13 \text{ TeV}$ is studied in the rapidity range ${2.0 < y < 4.5}$ and in the transverse momentum range ${6.5 < p_{T} < 14.0\text{ GeV}}$. The cross-section for prompt production of $\eta_c(1S)$ mesons relative to that of the $J/\psi$ meson is measured using the ${p\bar{p}}$ decay mode and is found to be ${\sigma_{\eta_c(1S)}/\sigma_{J/\psi} = 1.69 \pm 0.15 \pm 0.10 \pm 0.18}$. The quoted uncertainties are, in order, statistical, systematic and due to uncertainties on the branching fractions of the ${J/\psi\to p \bar{p}}$ and ${\eta_c\to p \bar{p}}$ decays. The prompt $\eta_c(1S)$ production cross-section is determined to be ${\sigma_{\eta_c(1S)} = 1.26 \pm 0.11\pm 0.08 \pm 0.14 \,\mu b}$, where the last uncertainty includes that on the ${J/\psi}$ meson cross-section. The ratio of the branching fractions of $b$-hadron decays to the $\eta_c(1S)$ and ${J/\psi}$ states is measured to be ${\mathcal{B}_{b\to\eta_c X}/\mathcal{B}_{b\to J/\psi X} = 0.48 \pm 0.03 \pm 0.03 \pm 0.05}$, where the last uncertainty is due to those on the branching fractions of the ${J/\psi \to p \bar{p}}$ and ${\eta_c\to p \bar{p}}$ decays. The difference between the ${J/\psi}$ and $\eta_c(1S)$ masses is also determined to be ${113.0 \pm 0.7 \pm 0.1\text{ MeV}}$, which is the most precise single measurement of this quantity to date.

The differential cross-section of prompt inclusive production of long-lived charged particles in proton-proton collisions is measured using a data sample recorded by the LHCb experiment at a centre-of-mass energy of ${\sqrt{s} = 13\,\mathrm{TeV}}$. The data sample, collected with an unbiased trigger, corresponds to an integrated luminosity of ${5.4\,\mathrm{nb}^{-1}}$. The differential cross-section is measured as a function of transverse momentum and pseudorapidity in the ranges ${p_\mathrm{T} \in [0.08, 10)\,\mathrm{GeV}\,c^{-1}}$ and ${\eta \in [2.0, 4.8)}$ and is determined separately for positively and negatively charged particles. The results are compared with predictions from various hadronic-interaction models.

The first observation of $Z$ boson production in proton-lead collisions at a centre-of-mass energy per proton-nucleon pair of $\sqrt{s_{NN}}=5~\text{TeV}$ is presented. The data sample corresponds to an integrated luminosity of $1.6~\text{nb}^{-1}$ collected with the LHCb detector. The $Z$ candidates are reconstructed from pairs of oppositely charged muons with pseudorapidities between 2.0 and 4.5 and transverse momenta above $20~\text{GeV}/c$. The invariant dimuon mass is restricted to the range $60-120~\text{GeV}/c^2$. The $Z$ production cross-section is measured to be \begin{eqnarray*} \sigma_{Z\to\mu^+\mu^-}(\text{fwd})&=&13.5^{+5.4}_{-4.0}\text{(stat.)}\pm1.2\text{(syst.)}~\text{nb} \end{eqnarray*} in the direction of the proton beam and \begin{eqnarray*} \sigma_{Z\to\mu^+\mu^-}(\text{bwd}) & =&10.7^{+8.4}_{-5.1}\text{(stat.)}\pm1.0\text{(syst.)}~\text{nb} \end{eqnarray*} in the direction of the lead beam, where the first uncertainty is statistical and the second systematic.

The inclusive $b \bar{b}$- and $c \bar{c}$-dijet production cross-sections in the forward region of $pp$ collisions are measured using a data sample collected with the LHCb detector at a centre-of-mass energy of 13 TeV in 2016. The data sample corresponds to an integrated luminosity of 1.6 fb$^{-1}$. Differential cross-sections are measured as a function of the transverse momentum and of the pseudorapidity of the leading jet, of the rapidity difference between the jets, and of the dijet invariant mass. A fiducial region for the measurement is defined by requiring that the two jets originating from the two $b$ or $c$ quarks are emitted with transverse momentum greater than 20 GeV$/c$, pseudorapidity in the range $2.2 < \eta < 4.2$, and with a difference in the azimuthal angle between the two jets greater than 1.5. The integrated $b \bar{b}$-dijet cross-section is measured to be $53.0 \pm 9.7$ nb, and the total $c \bar{c}$-dijet cross-section is measured to be $73 \pm 16$ nb. The ratio between $c \bar{c}$- and $b \bar{b}$-dijet cross-sections is also measured and found to be $1.37 \pm 0.27$. The results are in agreement with theoretical predictions at next-to-leading order.

The production of prompt charged particles in proton-lead collisions and in proton-proton collisions at the nucleon-nucleon centre-of-mass energy ${\sqrt{s_{\scriptscriptstyle\mathrm{NN}}}=5\,\mathrm{TeV}}$ is studied at LHCb as a function of pseudorapidity ($\eta$) and transverse momentum ($p_{\mathrm{T}}$) with respect to the proton beam direction. The nuclear modification factor for charged particles is determined as a function of $\eta$ between ${-4.8<\eta<-2.5}$ (backward region) and ${2.0<\eta<4.8}$ (forward region), and $p_{\mathrm{T}}$ between ${0.2<p_{\mathrm{T}}<8.0\,\mathrm{GeV}/c}$. The results show a suppression of charged particle production in proton-lead collisions relative to proton-proton collisions in the forward region and an enhancement in the backward region for $p_{\mathrm{T}}$ larger than $1.5\,\mathrm{GeV}/c$. This measurement constrains nuclear PDFs and saturation models at previously unexplored values of the parton momentum fraction down to $10^{-6}$.

Charm production at the LHC in pp collisions at sqrt(s)=7 TeV is studied with the LHCb detector. The decays D0 -> K- pi+, D+ -> K- pi+ pi+, D*+ -> D0(K- pi+) pi+, D_s+ -> phi(K- K+) pi+, Lambda_c+ -> p K- pi+, and their charge conjugates are analysed in a data set corresponding to an integrated luminosity of 15 nb^{-1}. Differential cross-sections dsigma/dp_T are measured for prompt production of the five charmed hadron species in bins of transverse momentum and rapidity in the region 0 < p_T < 8 GeV/c and 2.0 < y < 4.5. Theoretical predictions are compared to the measured differential cross-sections. The integrated cross-sections of the charm hadrons are computed in the above p_T-y range, and their ratios are reported. A combination of the five integrated cross-section measurements gives sigma(c\bar{c})_{p_T < 8 GeV/c, 2.0 < y < 4.5} = 1419 +/- 12 (stat) +/- 116 (syst) +/- 65 (frag) microbarn, where the uncertainties are statistical, systematic, and due to the fragmentation functions.