The observation of the production of four top quarks in proton-proton collisions is reported, based on a data sample collected by the CMS experiment at a center-of-mass energy of 13 TeV in 2016-2018 at the CERN LHC and corresponding to an integrated luminosity of 138 fb$^{-1}$. Events with two same-sign, three, or four charged leptons (electrons and muons) and additional jets are analyzed. Compared to previous results in these channels, updated identification techniques for charged leptons and jets originating from the hadronization of b quarks, as well as a revised multivariate analysis strategy to distinguish the signal process from the main backgrounds, lead to an improved expected signal significance of 4.9 standard deviations above the background-only hypothesis. Four top quark production is observed with a significance of 5.6 standard deviations, and its cross section is measured to be 17.7 $^{+3.7}_{-3.5}$ (stat) $^{+2.3}_{-1.9}$ (syst) fb, in agreement with the available standard model predictions.

A measurement of single top-quark production in the s-channel is performed in proton$-$proton collisions at a centre-of-mass energy of 13 TeV with the ATLAS detector at the CERN Large Hadron Collider. The dataset corresponds to an integrated luminosity of 139 fb$^{-1}$. The analysis is performed on events with an electron or muon, missing transverse momentum and exactly two $b$-tagged jets in the final state. A discriminant based on matrix element calculations is used to separate single-top-quark s-channel events from the main background contributions, which are top-quark pair production and $W$-boson production in association with jets. The observed (expected) signal significance over the background-only hypothesis is 3.3 (3.9) standard deviations, and the measured cross-section is $\sigma=8.2^{+3.5}_{-2.9}$ pb, consistent with the Standard Model prediction of $\sigma^{\mathrm{SM}}=10.32^{+0.40}_{-0.36}$ pb.

The results of a search for Higgs boson pair (HH) production in the WW*WW*, WW*$\tau\tau$, and $\tau\tau\tau\tau$ decay modes are presented. The search uses 138 fb$^{-1}$ of proton-proton collision data recorded by the CMS experiment at the LHC at a center-of-mass energy of 13 TeV from 2016 to 2018. Analyzed events contain two, three, or four reconstructed leptons, including electrons, muons, and hadronically decaying tau leptons. No evidence for a signal is found in the data. Upper limits are set on the cross section for nonresonant HH production, as well as resonant production in which a new heavy particle decays to a pair of Higgs bosons. For nonresonant production, the observed (expected) upper limit on the cross section at 95% confidence level (CL) is 21.3 (19.4) times the standard model (SM) prediction. The observed (expected) ratio of the trilinear Higgs boson self-coupling to its value in the SM is constrained to be within the interval $-$6.9 to 11.1 ($-$6.9 to 11.7) at 95% CL, and limits are set on a variety of new-physics models using an effective field theory approach. The observed (expected) limits on the cross section for resonant HH production range from 0.18 to 0.90 (0.08 to 1.06) pb at 95% CL for new heavy-particle masses in the range 250-1000 GeV.

A search for resonances decaying into a W boson and a radion, where the radion decays into two W bosons, is presented. The data analyzed correspond to an integrated luminosity of 138 fb$^{-1}$ recorded in proton-proton collisions with the CMS detector at $\sqrt{s} =$ 13 TeV. One isolated charged lepton is required, together with missing transverse momentum and one or two massive large-radius jets, containing the decay products of either two or one W bosons, respectively. No excess over the background estimation is observed. The results are combined with those from a complementary channel with an all-hadronic final state, described in an accompanying paper. Limits are set on parameters of an extended warped extra-dimensional model. These searches are the first of their kind at the LHC.

The production cross section of a top quark pair in association with a photon is measured in proton-proton collisions in the decay channel with two oppositely charged leptons (e$^\pm\mu^\mp$, e$^+$e$^-$, or $\mu^+\mu^-$). The measurement is performed using 138 fb$^{-1}$ of proton-proton collision data recorded by the CMS experiment at $\sqrt{s} =$ 13 TeV during the 2016-2018 data-taking period of the CERN LHC. A fiducial phase space is defined such that photons radiated by initial-state particles, top quarks, or any of their decay products are included. An inclusive cross section of 175.2 $\pm$ 2.5 (stat) $\pm$ 6.3 (syst) fb is measured in a signal region with at least one jet coming from the hadronization of a bottom quark and exactly one photon with transverse momentum above 20 GeV. Differential cross sections are measured as functions of several kinematic observables of the photon, leptons, and jets, and compared to standard model predictions. The measurements are also interpreted in the standard model effective field theory framework, and limits are found on the relevant Wilson coefficients from these results alone and in combination with a previous CMS measurement of the $\mathrm{t\bar{t}}\gamma$ production process using the lepton+jets final state.

A search for Kaluza-Klein excited vector boson resonances, $W_\mathrm{KK}$, decaying in cascade to three W bosons via a scalar radion $R, W_\mathrm{KK}\to WR \to WWW$, with two or three massive jets is presented. The search is performed with proton-proton collision data recorded at $\sqrt{s} =$ 13 TeV, collected by the CMS experiment at the CERN LHC, during 2016-2018, corresponding to an integrated luminosity of 138 fb$^{-1}$. Two final states are simultaneously probed, one where the two W bosons produced by the R decay are reconstructed as separate, large-radius, massive jets, and one where they are merged in a single large-radius jet. The observed data are in agreement with the standard model expectations. Limits are set on the product of the $W_\mathrm{KK}$ resonance cross section and branching fraction to three W bosons in an extended warped extra-dimensional model and are the first of their kind at the LHC.

The associated production of a Higgs boson and a top-quark pair is measured in events characterised by the presence of one or two electrons or muons. The Higgs boson decay into a $b$-quark pair is used. The analysed data, corresponding to an integrated luminosity of 139 fb$^{-1}$, were collected in proton-proton collisions at the Large Hadron Collider between 2015 and 2018 at a centre-of-mass energy of $\sqrt{s}=13$ TeV. The measured signal strength, defined as the ratio of the measured signal yield to that predicted by the Standard Model, is $0.35^{+0.36}_{-0.34}$. This result is compatible with the Standard Model prediction and corresponds to an observed (expected) significance of 1.0 (2.7) standard deviations. The signal strength is also measured differentially in bins of the Higgs boson transverse momentum in the simplified template cross-section framework, including a bin for specially selected boosted Higgs bosons with transverse momentum above 300 GeV.

Measurements of the total and differential fiducial cross sections for the Z boson decaying into two neutrinos are presented at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV. The data were collected by the CMS detector in 2016 and correspond to an integrated luminosity of 35.9 fb$^{-1}$. In these measurements, events are selected containing an imbalance in transverse momentum and one or more energetic jets. The fiducial differential cross section is measured as a function of the Z boson transverse momentum. The results are combined with a previous measurement of charged-lepton decays of the Z boson.

This paper describes a search for beyond the Standard Model decays of the Higgs boson into a pair of new spin-0 particles subsequently decaying into $b$-quark pairs, $H \rightarrow aa \rightarrow (b\bar{b})(b\bar{b})$, using proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider at center-of-mass energy $\sqrt{s}=13$ TeV. This search focuses on the regime where the decay products are collimated and in the range $15 \leq m_a \leq 30$ GeV and is complementary to a previous search in the same final state targeting the regime where the decay products are well separated and in the range $20 \leq m_a \leq 60$ GeV. A novel strategy for the identification of the $a \rightarrow b\bar{b}$ decays is deployed to enhance the efficiency for topologies with small separation angles. The search is performed with 36 fb$^{-1}$ of integrated luminosity collected in 2015 and 2016 and sets upper limits on the production cross-section of $H \rightarrow aa \rightarrow (b\bar{b})(b\bar{b})$, where the Higgs boson is produced in association with a $Z$ boson.

A search for heavy neutral Higgs bosons is performed using the LHC Run 2 data, corresponding to an integrated luminosity of 139 fb$^{-1}$ of proton-proton collisions at $\sqrt{s}=13$ TeV recorded with the ATLAS detector. The search for heavy resonances is performed over the mass range 0.2-2.5 TeV for the $\tau^+\tau^-$ decay with at least one $\tau$-lepton decaying into final states with hadrons. The data are in good agreement with the background prediction of the Standard Model. In the $M_{h}^{125}$ scenario of the Minimal Supersymmetric Standard Model, values of $\tan\beta>8$ and $\tan\beta>21$ are excluded at the 95% confidence level for neutral Higgs boson masses of 1.0 TeV and 1.5 TeV, respectively, where $\tan\beta$ is the ratio of the vacuum expectation values of the two Higgs doublets.