Inclusive $\Upsilon$(1S) and $\Upsilon$(2S) production have been measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair $\sqrt{s_{_{\rm NN}}}=5.02$ TeV, using the ALICE detector at the CERN LHC. The $\Upsilon$ mesons are reconstructed in the centre-of-mass rapidity interval $2.5<y<4$ and in the transverse-momentum range $p_{\rm T}<15$ GeV/$c$, via their decays to muon pairs. In this Letter, we present results on the inclusive $\Upsilon$(1S) nuclear modification factor $R_{\rm AA}$ as a function of collision centrality, transverse momentum and rapidity. The $\Upsilon$(1S) and $\Upsilon$(2S) $R_{\rm AA}$, integrated over the centrality range 0-90%, are $0.37 \pm 0.02 {\rm{(stat)}}\pm 0.03 {\rm{(syst)}}$ and $0.10 \pm 0.04 {\rm{(stat)}}\pm 0.02 {\rm{(syst)}}$, respectively, leading to a ratio $R_{\rm{AA}}^{\Upsilon(\rm2S)}/R_{\rm{AA}}^{\Upsilon(\rm1S)}$ of $0.28\pm0.12\text{(stat)}\pm0.06\text{(syst)}$. The observed $\Upsilon$(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.

The production of Z$^0$ bosons at large rapidities in Pb-Pb collisions at $\sqrt{s_{\rm NN}}=5.02$ TeV is reported. Z$^0$ candidates are reconstructed in the dimuon decay channel (${\rm Z}^0 \rightarrow \mu^+\mu^-$), based on muons selected with pseudo-rapidity $-4.0<\eta<-2.5$ and $p_{\rm T}>20$ GeV/$c$. The invariant yield and the nuclear modification factor, $R_{\rm AA}$, are presented as a function of rapidity and collision centrality. The value of $R_{\rm AA}$ for the 0-20% central Pb-Pb collisions is $0.67 \pm 0.11 \, \mbox{(stat.)} \, \pm 0.03 \, \mbox{(syst.)} \, \pm 0.06 \, \mbox{(corr. syst.)}$, exhibiting a deviation of $2.6 \sigma$ from unity. The results are well-described by calculations that include nuclear modifications of the parton distribution functions, while the predictions using vacuum PDFs deviate from data by $2.3\sigma$ in the 0-90% centrality class and by $3\sigma$ in the 0-20% central collisions.

We report the measured transverse momentum ($p_{\rm T}$) spectra of primary charged particles from pp, p-Pb and Pb-Pb collisions at a center-of-mass energy $\sqrt{s_{\rm NN}} = 5.02$ TeV in the kinematic range of $0.15<p_{\rm T}<50$ GeV/$c$ and $|\eta|< 0.8$. A significant improvement of systematic uncertainties motivated the reanalysis of data in pp and Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 2.76$ TeV, as well as in p-Pb collisions at $\sqrt{s_{\rm NN}} = 5.02$ TeV, which is also presented. Spectra from Pb-Pb collisions are presented in nine centrality intervals and are compared to a reference spectrum from pp collisions scaled by the number of binary nucleon-nucleon collisions. For central collisions, the $p_{\rm T}$ spectra are suppressed by more than a factor of 7 around 6-7 GeV/$c$ with a significant reduction in suppression towards higher momenta up to 30 GeV/$c$. The nuclear modification factor $R_{\rm pPb}$, constructed from the pp and p-Pb spectra measured at the same collision energy, is consistent with unity above 8 GeV/$c$. While the spectra in both pp and Pb-Pb collisions are substantially harder at $\sqrt{s_{\rm NN}} = 5.02$ TeV compared to 2.76 TeV, the nuclear modification factors show no significant collision energy dependence. The obtained results should provide further constraints on the parton energy loss calculations to determine the transport properties of the hot and dense QCD matter.

The production of $\Upsilon$ mesons in Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}}$ = 5 TeV is measured with the muon spectrometer of the ALICE detector at the LHC. The yields as well as the nuclear modification factors are determined in the forward rapidity region $2.5<y<4.0$, as a function of rapidity, transverse momentum and collision centrality. The results show that the production of the $\Upsilon$(1S) meson is suppressed by a factor of about three with respect to the production in proton-proton collisions. For the first time, a significant signal for the $\Upsilon$(2S) meson is observed at forward rapidity, indicating a suppression stronger by about a factor 2-3 with respect to the ground state. The measurements are compared with transport, hydrodynamic, comover and statistical hadronisation model calculations.

Transverse momentum ($p_{\rm T}$) spectra of charged particles at mid-pseudorapidity in Xe-Xe collisions at $\sqrt{s_{\rm NN}}$ = 5.44 TeV measured with the ALICE apparatus at the Large Hadron Collider are reported. The kinematic range $0.15 < p_{\rm T} < 50$ GeV/$c$ and $|\eta| < 0.8$ is covered. Results are presented in nine classes of collision centrality in the 0-80% range. For comparison, a pp reference at the collision energy of $\sqrt{s}$ = 5.44 TeV is obtained by interpolating between existing \pp measurements at $\sqrt{s}$ = 5.02 and 7 TeV. The nuclear modification factors in central Xe-Xe collisions and Pb-Pb collisions at a similar center-of-mass energy of $\sqrt{s_{\rm NN}}$ = 5.02 TeV, and in addition at 2.76 TeV, at analogous ranges of charged particle multiplicity density $\left\langle\rm{d}N_{\rm ch}/\rm{d}\eta\right\rangle$ show a remarkable similarity at $p_{\rm T}> 10$ GeV/$c$. The comparison of the measured $R_{\rm AA}$ values in the two colliding systems could provide insight on the path length dependence of medium-induced parton energy loss. The centrality dependence of the ratio of the average transverse momentum $\left\langle p_{\rm{T}}\right\rangle$ in Xe-Xe collisions over Pb-Pb collision at $\sqrt{s}$ = 5.02 TeV is compared to hydrodynamical model calculations.

The production of non-prompt ${\rm D}^{0}$ mesons from beauty-hadron decays was measured at midrapidity ($\left| y \right| < 0.5$) in Pb-Pb collisions at a nucleon-nucleon center-of-mass energy of $\sqrt{s_{\rm NN}}=5.02~\mathrm{TeV}$ with the ALICE experiment at the LHC. Their nuclear modification factor ($R_{\rm AA}$), measured for the first time down to $p_{\rm T}=1~\mathrm{GeV}/c$ in the $0-10$% and $30-50$% centrality classes, indicates a significant suppression, up to a factor of about three, for $p_{\rm T} > 5~\mathrm{GeV}/c$ in the $0-10$% central Pb-Pb collisions. The data are described by models that include both collisional and radiative processes in the calculation of beauty-quark energy loss in the quark-gluon plasma, and quark recombination in addition to fragmentation as a hadronisation mechanism. The ratio of the non-prompt to prompt ${\rm D}^{0}$-meson $R_{\rm AA}$ is larger than unity for $p_{\rm T} > 4~\mathrm{GeV}/c$ in the $0-10$% central Pb-Pb collisions, as predicted by models in which beauty quarks lose less energy than charm quarks in the quark-gluon plasma because of their larger mass.

The production yield and angular anisotropy of prompt ${D_s^+}$ mesons were measured as a function of transverse momentum ($p_{ T}$) in Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{ NN}} = 5.02$ TeV collected with the ALICE detector at the LHC. ${D_s^+}$ mesons and their charge conjugates were reconstructed at midrapidity ($|y|<0.5$) from their hadronic decay channel ${D_s^+ \to \phi \pi^+}$, with ${\phi \to K^-K^+}$, in the $p_{ T}$ intervals $2<p_{ T}<50$ GeV/$c$ and $2<p_{ T}<36$ GeV/$c$ for the 0-10% and 30-50% centrality intervals. For $p_{ T}>10$ GeV/$c$, the measured ${D_s^+}$-meson nuclear modification factor $R_{ AA}$ is consistent with the one of non-strange D mesons within uncertainties, while at lower $p_{ T}$ a hint for a ${D_s^+}$-meson $R_{ AA}$ larger than that of non-strange D mesons is seen. The enhanced production of ${D_s^+}$ relative to non-strange D mesons is also studied by comparing the $p_{ T}$-dependent ${D_s^+/D^0}$ production yield ratios in Pb-Pb and in pp collisions. The ratio measured in Pb-Pb collisions is found to be on average higher than that in pp collisions in the interval $2<p_{ T} <8$ GeV/$c$ with a significance of 2.3$\sigma$ and 2.4$\sigma$ for the 0-10% and 30-50% centrality intervals. The azimuthal anisotropy coefficient $v_2$ of prompt ${D_s^+}$ mesons was measured in Pb-Pb collisions in the 30-50% centrality interval and is found to be compatible with that of non-strange D mesons. The main features of the measured $R_{ AA}$, ${D_s^+/D^0}$ ratio, and $v_2$ as a function of $p_{ T}$ are described by theoretical calculations of charm-quark transport in a hydrodynamically expanding quark-gluon plasma including hadronisation via charm-quark recombination with light quarks from the medium. The $p_{ T}$-integrated production yield of ${D_s^+}$ mesons is compatible with the prediction of the statistical hadronisation model.

The inclusive J/$\psi$ meson production in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon collision of $\sqrt{s_{\rm NN}}$ = 5.02 TeV at midrapidity ($|y|$ < 0.9) is reported by the ALICE Collaboration. The measurements are performed in the dielectron decay channel, as a function of event centrality and J/$\psi$ transverse momentum $p_{\rm T}$, down to $p_{\rm T}$ = 0 GeV/$c$. The J/$\psi$ mean transverse momentum $\langle p_{\rm T} \rangle$ and $r_{\rm AA}$ ratio, defined as $\langle p^{\rm 2}_{\rm T} \rangle_{\rm PbPb}/\langle p^{\rm 2}_{\rm T} \rangle_{\rm pp}$, are evaluated. Both observables show a centrality dependence decreasing towards central (head-on) collisions. The J/$\psi$ nuclear modification factor $R_{\rm AA}$ exhibits a strong $p_{\rm T}$ dependence with a large suppression at high $p_{\rm T}$ and an increase to unity for decreasing $p_{\rm T}$. When integrating over the measured momentum range $p_{\rm T}$ < 10 GeV/$c$, the J/$\psi$ $R_{\rm AA}$ shows a weak centrality dependence. Each measurement is compared with results at lower center-of-mass energies and with ALICE measurements at forward rapidity, as well as to theory calculations. All reported features of the J/$\psi$ production at low $p_{\rm T}$ are consistent with a dominant contribution to the J/$\psi$ yield originating from charm quark (re)combination.

The production of prompt $\rm \Lambda_{\rm c}^{+}$ baryons at midrapidity ($|y|<0.5$) was measured in central (0-10%) and mid-central (30-50%) Pb-Pb collisions at the center-of-mass energy per nucleon-nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the ALICE detector. The results are more precise, more differential in centrality, and reach much lower transverse momentum ($p_{\rm T}=1$ GeV/$c$) with respect to previous measurements performed by the ALICE, STAR, and CMS Collaborations in nucleus-nucleus collisions, allowing for an extrapolation down to $p_{\rm T}=0$. The $p_{\rm T}$-differential $\rm \Lambda_{\rm c}^{+}$/D$^0$ production ratio is enhanced with respect to the pp measurement for $4<p_{\rm T}<8$ GeV/$c$ by 3.7 standard deviations ($\sigma$), while the $p_{\rm T}$-integrated ratios are compatible within 1$\sigma$. The observed trend is similar to that observed in the strange sector for the $\Lambda/$K$^0_{\rm S}$ ratio. Model calculations including coalescence or statistical hadronization for charm-hadron formation are compared with the data.

Measurements of the production of muons from heavy-flavour hadron decays in Pb$-$Pb collisions at $\sqrt{s_{\rm NN}}$ = $5.02$ and $2.76$ TeV using the ALICE detector at the LHC are reported. The nuclear modification factor $R_{\rm AA}$ at $\sqrt{s_{\rm NN}}$ = 5.02 TeV is measured at forward rapidity ($2.5 < y <4$) as a function of transverse momentum $p_{\rm T}$ in central, semi-central, and peripheral collisions over a wide $p_{\rm T}$ interval, $3 < p_{\rm T} < 20$ GeV/$c$, in which muons from beauty-hadron decays are expected to take over from charm as the dominant source at high $p_{\rm T}$ ($p_{\rm T} > 7$ GeV/$c$). The $R_{\rm AA}$ shows an increase of the suppression of the yields of muons from heavy-flavour hadron decays with increasing centrality. A suppression by a factor of about three is observed in the $10\%$ most central collisions. The $R_{\rm AA}$ at $\sqrt{s_{\rm NN}}$ = 5.02 is similar to that at 2.76 TeV. The precise $R_{\rm AA}$ measurements have the potential to distinguish between model predictions implementing different mechanisms of parton energy loss in the high-density medium formed in heavy-ion collisions. They place important constraints for the understanding of the heavy-quark interaction with the hot and dense QCD medium.

A measurement of $J/\psi$ and $\psi(2\mathrm{S})$ production is presented. It is based on a data sample from Pb+Pb collisions at $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV and $pp$ collisions at $\sqrt{s}$ = 5.02 TeV recorded by the ATLAS detector at the LHC in 2015, corresponding to an integrated luminosity of $0.42\mathrm{nb}^{-1}$ and $25\mathrm{pb}^{-1}$ in Pb+Pb and $pp$, respectively. The measurements of per-event yields, nuclear modification factors, and non-prompt fractions are performed in the dimuon decay channel for $9 < p_{T}^{\mu\mu} < 40$ GeV in dimuon transverse momentum, and $-2.0 < y_{\mu\mu} < 2.0$ in rapidity. Strong suppression is found in Pb+Pb collisions for both prompt and non-prompt $J/\psi$, as well as for prompt and non-prompt $\psi(2\mathrm{S})$, increasing with event centrality. The suppression of prompt $\psi(2\mathrm{S})$ is observed to be stronger than that of $J/\psi$, while the suppression of non-prompt $\psi(2\mathrm{S})$ is equal to that of the non-prompt $J/\psi$ within uncertainties, consistent with the expectation that both arise from \textit{b}-quarks propagating through the medium. Despite prompt and non-prompt $J/\psi$ arising from different mechanisms, the dependence of their nuclear modification factors on centrality is found to be quite similar.

The nuclear modification factors of J/$\psi$ and $\psi$(2S) mesons are measured in PbPb collisions at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}} =$ 5.02 TeV. The analysis is based on PbPb and pp data samples collected by CMS at the LHC in 2015, corresponding to integrated luminosities of 464 $\mu$b$^{-1}$ and 28 pb$^{-1}$, respectively. The measurements are performed in the dimuon rapidity range of $|y| <$ 2.4 as a function of centrality, rapidity, and transverse momentum (p$_\mathrm{T}$) from p$_\mathrm{T}=$ 3 GeV/$c$ in the most forward region and up to 50 GeV/$c$. Both prompt and nonprompt (coming from b hadron decays) mesons are observed to be increasingly suppressed with centrality, with a magnitude similar to the one observed at $\sqrt{s_{\mathrm{NN}}}=$ 2.76 TeV for the two J/$\psi$ meson components. No dependence on rapidity is observed for either prompt or nonprompt J/$\psi$ mesons. An indication of a lower prompt J/$\psi$ meson suppression at p$_\mathrm{T} >$ 25 GeV/$c$ is seen with respect to that observed at intermediate p$_\mathrm{T}$. The prompt $\psi$(2S) meson yield is found to be more suppressed than that of the prompt J/$\psi$ mesons in the entire p$_\mathrm{T}$ range.

Jet production in lead-lead (PbPb) and proton-proton (pp) collisions at a nucleon-nucleon center-of-mass energy of 5.02 TeV is studied with the CMS detector at the LHC, using PbPb and pp data samples corresponding to integrated luminosities of 404 $\mu$b$^{-1}$ and 27.4 pb$^{-1}$, respectively. Jets with different areas are reconstructed using the anti-$k_\mathrm{T}$ algorithm by varying the distance parameter $R$. The measurements are performed using jets with transverse momenta ($p_\mathrm{T}$) greater than 200 GeV and in a pseudorapidity range of $|\eta|$$\lt$ 2. To reveal the medium modification of the jet spectra in PbPb collisions, the properly normalized ratio of spectra from PbPb and pp data is used to extract jet nuclear modification factors as functions of the PbPb collision centrality, $p_\mathrm{T}$ and, for the first time, as a function of $R$ up to 1.0. For the most central collisions, a strong suppression is observed for high-$p_\mathrm{T}$ jets reconstructed with all distance parameters, implying that a significant amount of jet energy is scattered to large angles. The dependence of jet suppression on $R$ is expected to be sensitive to both the jet energy loss mechanism and the medium response, and so the data are compared to several modern event generators and analytic calculations. The models considered do not fully reproduce the data.

The transverse momentum ($p_\mathrm{t}$) spectrum of prompt D$^0$ mesons and their antiparticles has been measured via the hadronic decay channels D$^0 \to \mathrm{K}^- \pi^+$ and $\overline{\mathrm{D}}^0 \to \mathrm{K}^+ \pi^-$ in pp and PbPb collisions at a centre-of-mass energy of 5.02 TeV per nucleon pair with the CMS detector at the LHC. The measurement is performed in the D$^0$ meson $p_\mathrm{t}$ range of 2-100 GeV and in the rapidity range of $|y| < $1. The pp (PbPb) dataset used for this analysis corresponds to an integrated luminosity of 27.4 pb$^{-1}$ (530 $\mu$b$^{-1}$). The measured D$^0$ meson $p_\mathrm{t}$ spectrum in pp collisions is well described by perturbative QCD calculations. The nuclear modification factor, comparing D$^0$ meson yields in PbPb and pp collisions, was extracted for both minimum-bias and the 10% most central PbPb interactions. For central events, the D$^0$ meson yield in the PbPb collisions is suppressed by a factor of 5-6 compared to the pp reference in the $p_\mathrm{t}$ range of 6-10 GeV. For D$^0$ mesons in the high-$p_\mathrm{t}$ range of 60-100 GeV, a significantly smaller suppression is observed. The results are also compared to theoretical calculations.

The transverse energy ($E_\mathrm{T}^{\gamma}$) spectra of photons isolated from other particles are measured using proton-proton (pp) and lead-lead (PbPb) collisions at the LHC at $\sqrt{s_\mathrm{NN}} =$ 5.02 TeV with integrated luminosities of 27.4 pb$^{-1}$and 404 $\mu$b$^{-1}$ for pp and PbPb data, respectively. The results are presented for photons with 25 $<$ $E_\mathrm{T}^{\gamma}$ $<$ 200 GeV in the pseudorapidity range $|\eta|$ $<$ 1.44, and for different centrality intervals for PbPb collisions. Photon production in PbPb collisions is consistent with that in pp collisions scaled by the number of binary nucleon-nucleon collisions, demonstrating that photons do not interact with the quark-gluon plasma. Therefore, isolated photons can provide information about the initial energy of the associated parton in photon+jet measurements. The results are compared with predictions from the next-to-leading-order JETPHOX generator for different parton distribution functions (PDFs) and nuclear PDFs (nPDFs). The comparisons can help to constrain the nPDFs global fits.

The $B_\mathrm{c}^+$ meson is observed for the first time in heavy ion collisions. Data from the CMS detector are used to study the production of the $B_\mathrm{c}^+$ meson in lead-lead (PbPb) and proton-proton (pp) collisions at a center-of-mass energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}} =$ 5.02 TeV, via the $B_\mathrm{c}^+ \to (J/\psi\to\mu^+\mu^-)\mu^+\nu_\mu$ decay. The $B_\mathrm{c}^+$ nuclear modification factor, derived from the PbPb-to-pp ratio of production cross sections, is measured in two bins of the trimuon transverse momentum and of the PbPb collision centrality. The B$_\mathrm{c}^+$ meson is shown to be less suppressed than quarkonia and most of the open heavy-flavor mesons, suggesting that effects of the hot and dense nuclear matter created in heavy ion collisions contribute to its production. This measurement sets forth a promising new probe of the interplay of suppression and enhancement mechanisms in the production of heavy-flavor mesons in the quark-gluon plasma.

The differential cross sections of $\Lambda_\mathrm{c}^+$ baryon production are measured via the exclusive decay channel $\Lambda_\mathrm{c}^+ \to $pK$^-\pi^+$, as a function of transverse momentum ($p_\mathrm{T}$) in proton-proton (pp) and lead-lead (PbPb) collisions at a nucleon-nucleon center-of-mass energy of 5.02 TeV with the CMS detector at the LHC. The measurement is performed within the $\Lambda_\mathrm{c}^+$ rapidity interval $|y|<$1.0 in the $p_\mathrm{T}$ range of 5-20 GeV/$c$ in pp and 10-20 GeV/$c$ in PbPb collisions. The observed yields of $\Lambda_\mathrm{c}^+$ for $p_\mathrm{T}$ of 10-20 GeV/$c$ suggest a possible suppression in central PbPb collisions compared to pp collisions. The $\Lambda_\mathrm{c}^+/$D$^0$ production ratio in pp collisions is compared to theoretical models. In PbPb collisions, this ratio is consistent with the result from pp collisions in their common $p_\mathrm{T}$ range.

The production of $\Upsilon$(2S) and $\Upsilon$(3S) mesons in lead-lead (PbPb) and proton-proton (pp) collisions is studied in their dimuon decay channel using the CMS detector at the LHC. The $\Upsilon$(3S) meson is observed for the first time in PbPb collisions, with a significance above five standard deviations. The ratios of yields measured in PbPb and pp collisions are reported for both the $\Upsilon$(2S) and $\Upsilon$(3S) mesons, as functions of transverse momentum and PbPb collision centrality. These ratios, when appropriately scaled, are significantly less than unity, indicating a suppression of $\Upsilon$ yields in PbPb collisions. This suppression increases from peripheral to central PbPb collisions. Furthermore, the suppression is stronger for $\Upsilon$(3S) mesons compared to $\Upsilon$(2S) mesons, extending the pattern of sequential suppression of quarkonium states in nuclear collisions previously seen for the $\psi$/J, $\psi$(2S), $\Upsilon$(1S), and $\Upsilon$(2S) mesons.

Measurements of the yield and nuclear modification factor, $R_\mathrm{ AA}$, for inclusive jet production are performed using 0.49 nb$^{-1}$ of Pb+Pb data at $\sqrt{s_\mathrm{NN}} = 5.02$ TeV and 25 pb$^{-1}$ of $pp$ data at $\sqrt{s}=5.02$ TeV with the ATLAS detector at the LHC. Jets are reconstructed with the anti-$k_t$ algorithm with radius parameter $R=0.4$ and are measured over the transverse momentum range of 40-1000 GeV in six rapidity intervals covering $|y|<2.8$. The magnitude of $R_\mathrm{ AA}$ increases with increasing jet transverse momentum, reaching a value of approximately 0.6 at 1 TeV in the most central collisions. The magnitude of $R_\mathrm{ AA}$ also increases towards peripheral collisions. The value of $R_\mathrm{ AA}$ is independent of rapidity at low jet transverse momenta, but it is observed to decrease with increasing rapidity at high transverse momenta.

The cross sections for $\Upsilon$(1S), $\Upsilon$(2S), and $\Upsilon$(3S) production in lead-lead (PbPb) and proton-proton (pp) collisions at $\sqrt{s_{_\mathrm{NN}}} =$ 5.02 TeV have been measured using the CMS detector at the LHC. The nuclear modification factors, R$_\mathrm{AA}$, derived from the PbPb-to-pp ratio of yields for each state, are studied as functions of meson rapidity and transverse momentum, as well as PbPb collision centrality. The yields of all three states are found to be significantly suppressed, and compatible with a sequential ordering of the suppression, R$_\mathrm{AA}$($\Upsilon$(1S)) $>$ R$_\mathrm{AA}$($\Upsilon$(2S)) $>$ R$_\mathrm{AA}$($\Upsilon$(3S)) . The suppression of $\Upsilon$(1S) is larger than that seen at $\sqrt{s_{_\mathrm{NN}}} =$ 2.76 TeV, although the two are compatible within uncertainties. The upper limit on the R$_\mathrm{AA}$ of $\Upsilon$(3S) integrated over $p_\mathrm{T}$ and rapidity is 0.094 at 95% confidence level, which is the strongest suppression observed for any hadron species in heavy ion collisions to date.

The production of prompt $\Lambda^+_\mathrm{c}$ baryons is measured via the exclusive decay channel $\Lambda^+_\mathrm{c}$$\to$ pK$^-\pi^+$ at a center-of-mass energy per nucleon pair of 5.02 TeV, using proton-proton (pp) and lead-lead (PbPb) collision data collected by the CMS experiment at the CERN LHC. The pp and PbPb data were obtained in 2017 and 2018 with integrated luminosities of 252 and 0.607 nb$^{-1}$, respectively. The measurements are performed within the $\Lambda^+_\mathrm{c}$ rapidity interval $\vert y \vert$$\lt$ 1 with transverse momentum ($p_\mathrm{T}$) ranges of 3-30 and 6-40 GeV/$c$ for pp and PbPb collisions, respectively. Compared to the yields in pp collisions scaled by the expected number of nucleon-nucleon interactions, the observed yields of $\Lambda^+_\mathrm{c}$ with $p_\mathrm{T}$$\gt$ 10 GeV/$c$ are strongly suppressed in PbPb collisions. The level of suppression depends significantly on the collision centrality. The $\Lambda^+_\mathrm{c}$ / D$^0$ production ratio is similar in PbPb and pp collisions at $p_\mathrm{T}$$\gt$ 10 GeV/$c$, suggesting that the coalescence process does not play a dominant role in prompt $\Lambda^+_\mathrm{c}$ baryon production at higher $p_\mathrm{T}$.