Production cross-sections of prompt charm mesons are measured using data from $pp$ collisions at the LHC at a centre-of-mass energy of $5\,$TeV. The data sample corresponds to an integrated luminosity of $8.60\pm0.33\,$pb$^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^0$, $D^+$, $D_s^+$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\text{T}}$, and rapidity, $y$. They cover the rapidity range $2.0<y<4.5$ and transverse momentum ranges $0 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D^0$ and $D^+$ and $1 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D_s^+$ and $D^{*+}$ mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of $1 < p_{\text{T}} < 8\, \text{GeV}/c$ are determined to be \sigma(pp\rightarrow D^0 X) = 1004 \pm 3 \pm 54\,\mu\text{b} \sigma(pp\rightarrow D^+ X) = 402 \pm 2 \pm 30\,\mu\text{b} \sigma(pp\rightarrow D_s^+ X) = 170 \pm 4 \pm 16\,\mu\text{b} \sigma(pp\rightarrow D^{*+} X)= 421 \pm 5 \pm 36\,\mu\text{b} where the uncertainties are statistical and systematic, respectively.

The production of $J/\psi$ mesons in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=13$ TeV is studied with the \lhcb detector. Cross-section measurements are performed as a function of the transverse momentum $p_\mathrm{T}$ and the rapidity $y$ of the $J/\psi$ meson in the region $p_\mathrm{T}<14\mathrm{GeV}/c$ and $2.0<y<4.5$, for both prompt $J/\psi$ mesons and $J/\psi$ mesons from $b$-hadron decays. The production cross-sections integrated over the kinematic coverage are $15.03\pm 0.03\pm 0.94$ $\mu$b for prompt $J/\psi$ and $2.25\pm 0.01\pm 0.14$ $\mu$b for $J/\psi$ from $b$-hadron decays, assuming zero polarization of the $J/\psi$ meson. The first uncertainties are statistical and the second systematic. The cross-section reported for $J/\psi$ mesons from $b$-hadron decays is used to extrapolate to a total $b\bar{b}$ cross-section. The ratios of the cross-sections with respect to $\sqrt{s}=8$ TeV are also determined.

Production cross-sections of prompt charm mesons are measured with the first data from $pp$ collisions at the LHC at a centre-of-mass energy of $13\,\mathrm{TeV}$. The data sample corresponds to an integrated luminosity of $4.98 \pm 0.19\,\mathrm{pb}^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^{0}$, $D^{+}$, $D_{s}^{+}$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\mathrm{T}}$, and rapidity, $y$, and cover the range $0 < p_{\mathrm{T}} < 15\,\mathrm{GeV}/c$ and $2.0 < y < 4.5$. The inclusive cross-sections for the four mesons, including charge conjugation, within the range of $1 < p_{\mathrm{T}} < 8\,\mathrm{GeV}/c$ are found to be \begin{equation} \sigma(pp \to D^{0} X) = 2072 \pm 2 \pm 124\,\mu\mathrm{b}\\ \sigma(pp \to D^{+} X) = 834 \pm 2 \pm \phantom{1}78\,\mu\mathrm{b}\\ \sigma(pp \to D_{s}^{+} X) = 353 \pm 9 \pm \phantom{1}76\,\mu\mathrm{b}\\ \sigma(pp \to D^{*+} X) = 784 \pm 4 \pm \phantom{1}87\,\mu\mathrm{b} \end{equation} where the uncertainties are due to statistical and systematic uncertainties, respectively.

The production of $B^{\pm}$ mesons is studied in $pp$ collisions at centre-of-mass energies of 7 and 13 TeV, using $B^{\pm}\rightarrow J/\psi K^{\pm}$ decays and data samples corresponding to 1.0 fb$^{-1}$ and 0.3 fb$^{-1}$, respectively. The production cross-sections summed over both charges and integrated over the transverse momentum range $0<p_{\text{T}}< 40$ GeV/$c$ and the rapidity range $2.0<y<4.5$ are measured to be $\sigma(pp \rightarrow B^{\pm} X, \sqrt{s} = \text{7 TeV}) = 43.0 \pm 0.2 \pm 2.5 \pm 1.7\mu b,$ $\sigma(pp \rightarrow B^{\pm} X, \sqrt{s} = \text{13 TeV}) = 86.6 \pm 0.5 \pm 5.4 \pm 3.4\mu b,$ where the first uncertainties are statistical, the second are systematic, and the third are due to the limited knowledge of the $B^{\pm}\rightarrow J/\psi K^{\pm}$ branching fraction. The ratio of the cross-section at 13 TeV to that at 7 TeV is determined to be $2.02\pm0.02\text{(stat)}\pm0.12\text{(syst)}$. Differential cross-sections are also reported as functions of $p_{\text{T}}$ and $y$. All results are in agreement with theoretical calculations based on the state-of-art fixed next-to-leading order quantum chromodynamics.

The production cross-sections of $J/\psi$ mesons in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=5$ TeV are measured using a data sample corresponding to an integrated luminosity of $9.13\pm0.18~\text{pb}^{-1}$, collected by the LHCb experiment. The cross-sections are measured differentially as a function of transverse momentum, $p_{\text{T}}$, and rapidity, $y$, and separately for $J/\psi$ mesons produced promptly and from beauty hadron decays (nonprompt). With the assumption of unpolarised $J/\psi$ mesons, the production cross-sections integrated over the kinematic range $0<p_{\text{T}}<20~\text{GeV}/c$ and $2.0<y<4.5$ are $8.154\pm0.010\pm0.283~\mu\text{b}$ for prompt $J/\psi$ mesons and $0.820\pm0.003\pm0.034~\mu\text{b}$ for nonprompt $J/\psi$ mesons, where the first uncertainties are statistical and the second systematic. These cross-sections are compared with those at $\sqrt{s}=8$ TeV and $13$ TeV, and are used to update the measurement of the nuclear modification factor in proton-lead collisions for $J/\psi$ mesons at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\text{NN}}}=5$ TeV. The results are compared with theoretical predictions.

Measurements of differential cross sections are presented for inclusive isolated-photon production in $pp$ collisions at a centre-of-mass energy of 13 TeV provided by the LHC and using 139 fb$^{-1}$ of data recorded by the ATLAS experiment. The cross sections are measured as functions of the photon transverse energy in different regions of photon pseudorapidity. The photons are required to be isolated by means of a fixed-cone method with two different cone radii. The dependence of the inclusive-photon production on the photon isolation is investigated by measuring the fiducial cross sections as functions of the isolation-cone radius and the ratios of the differential cross sections with different radii in different regions of photon pseudorapidity. The results presented in this paper constitute an improvement with respect to those published by ATLAS earlier: the measurements are provided for different isolation radii and with a more granular segmentation in photon pseudorapidity that can be exploited in improving the determination of the proton parton distribution functions. These improvements provide a more in-depth test of the theoretical predictions. Next-to-leading-order QCD predictions from JETPHOX and SHERPA and next-to-next-to-leading-order QCD predictions from NNLOJET are compared to the measurements, using several parameterisations of the proton parton distribution functions. The measured cross sections are well described by the fixed-order QCD predictions within the experimental and theoretical uncertainties in most of the investigated phase-space region.

A measurement of single top-quark production in the s-channel is performed in proton$-$proton collisions at a centre-of-mass energy of 13 TeV with the ATLAS detector at the CERN Large Hadron Collider. The dataset corresponds to an integrated luminosity of 139 fb$^{-1}$. The analysis is performed on events with an electron or muon, missing transverse momentum and exactly two $b$-tagged jets in the final state. A discriminant based on matrix element calculations is used to separate single-top-quark s-channel events from the main background contributions, which are top-quark pair production and $W$-boson production in association with jets. The observed (expected) signal significance over the background-only hypothesis is 3.3 (3.9) standard deviations, and the measured cross-section is $\sigma=8.2^{+3.5}_{-2.9}$ pb, consistent with the Standard Model prediction of $\sigma^{\mathrm{SM}}=10.32^{+0.40}_{-0.36}$ pb.

The ratio of the cross sections for inclusive isolated-photon production in $pp$ collisions at centre-of-mass energies of 13 and 8 TeV is measured using the ATLAS detector at the LHC. The integrated luminosities of the 13 TeV and 8 TeV datasets are 3.2 fb$^{-1}$ and 20.2 fb$^{-1}$, respectively. The ratio is measured as a function of the photon transverse energy in different regions of the photon pseudorapidity. The predictions from next-to-leading-order perturbative QCD calculations are compared with the measured ratio. The experimental systematic uncertainties as well as the uncertainties affecting the predictions are evaluated taking into account the correlations between the two centre-of-mass energies, resulting in a reduction of up to a factor of $2.5$ ($5$) in the experimental (theoretical) systematic uncertainties. The predictions based on several parameterisations of the proton parton distribution functions agree with the data within the reduced experimental and theoretical uncertainties. In addition, this ratio to that of the fiducial cross sections for $Z$ boson production at 13 and 8 TeV using the decay channels $Z \rightarrow e^+e^-$ and $Z \rightarrow \mu^+\mu^-$ is made and compared with the theoretical predictions. In this double ratio, a further reduction of the experimental uncertainty is obtained because the uncertainties arising from the luminosity measurement cancel out. The predictions describe the measurements of the double ratio within the theoretical and experimental uncertainties.

Measurements of the differential production cross-sections of prompt and non-prompt $J/\psi$ and $\psi(2$S$)$ mesons with transverse momenta between 8 and 360 GeV and rapidity in the range $|y|<2$ are reported. Furthermore, measurements of the non-prompt fractions of $J/\psi$ and $\psi(2$S$)$, and the prompt and non-prompt $\psi(2$S$)$-to-$J/\psi$ production ratios, are presented. The analysis is performed using 140 fb$^{-1}$ of $\sqrt{s}=13$ TeV $pp$ collision data recorded by the ATLAS detector at the LHC during the years 2015-2018.

The associated production of a Higgs boson and a top-quark pair is measured in events characterised by the presence of one or two electrons or muons. The Higgs boson decay into a $b$-quark pair is used. The analysed data, corresponding to an integrated luminosity of 139 fb$^{-1}$, were collected in proton-proton collisions at the Large Hadron Collider between 2015 and 2018 at a centre-of-mass energy of $\sqrt{s}=13$ TeV. The measured signal strength, defined as the ratio of the measured signal yield to that predicted by the Standard Model, is $0.35^{+0.36}_{-0.34}$. This result is compatible with the Standard Model prediction and corresponds to an observed (expected) significance of 1.0 (2.7) standard deviations. The signal strength is also measured differentially in bins of the Higgs boson transverse momentum in the simplified template cross-section framework, including a bin for specially selected boosted Higgs bosons with transverse momentum above 300 GeV.