The production of $\Upsilon$(2S) and $\Upsilon$(3S) mesons in lead-lead (PbPb) and proton-proton (pp) collisions is studied in their dimuon decay channel using the CMS detector at the LHC. The $\Upsilon$(3S) meson is observed for the first time in PbPb collisions, with a significance above five standard deviations. The ratios of yields measured in PbPb and pp collisions are reported for both the $\Upsilon$(2S) and $\Upsilon$(3S) mesons, as functions of transverse momentum and PbPb collision centrality. These ratios, when appropriately scaled, are significantly less than unity, indicating a suppression of $\Upsilon$ yields in PbPb collisions. This suppression increases from peripheral to central PbPb collisions. Furthermore, the suppression is stronger for $\Upsilon$(3S) mesons compared to $\Upsilon$(2S) mesons, extending the pattern of sequential suppression of quarkonium states in nuclear collisions previously seen for the $\psi$/J, $\psi$(2S), $\Upsilon$(1S), and $\Upsilon$(2S) mesons.

The production of prompt $\Lambda^+_\mathrm{c}$ baryons is measured via the exclusive decay channel $\Lambda^+_\mathrm{c}$$\to$ pK$^-\pi^+$ at a center-of-mass energy per nucleon pair of 5.02 TeV, using proton-proton (pp) and lead-lead (PbPb) collision data collected by the CMS experiment at the CERN LHC. The pp and PbPb data were obtained in 2017 and 2018 with integrated luminosities of 252 and 0.607 nb$^{-1}$, respectively. The measurements are performed within the $\Lambda^+_\mathrm{c}$ rapidity interval $\vert y \vert$$\lt$ 1 with transverse momentum ($p_\mathrm{T}$) ranges of 3-30 and 6-40 GeV/$c$ for pp and PbPb collisions, respectively. Compared to the yields in pp collisions scaled by the expected number of nucleon-nucleon interactions, the observed yields of $\Lambda^+_\mathrm{c}$ with $p_\mathrm{T}$$\gt$ 10 GeV/$c$ are strongly suppressed in PbPb collisions. The level of suppression depends significantly on the collision centrality. The $\Lambda^+_\mathrm{c}$ / D$^0$ production ratio is similar in PbPb and pp collisions at $p_\mathrm{T}$$\gt$ 10 GeV/$c$, suggesting that the coalescence process does not play a dominant role in prompt $\Lambda^+_\mathrm{c}$ baryon production at higher $p_\mathrm{T}$.

The $B_\mathrm{c}^+$ meson is observed for the first time in heavy ion collisions. Data from the CMS detector are used to study the production of the $B_\mathrm{c}^+$ meson in lead-lead (PbPb) and proton-proton (pp) collisions at a center-of-mass energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}} =$ 5.02 TeV, via the $B_\mathrm{c}^+ \to (J/\psi\to\mu^+\mu^-)\mu^+\nu_\mu$ decay. The $B_\mathrm{c}^+$ nuclear modification factor, derived from the PbPb-to-pp ratio of production cross sections, is measured in two bins of the trimuon transverse momentum and of the PbPb collision centrality. The B$_\mathrm{c}^+$ meson is shown to be less suppressed than quarkonia and most of the open heavy-flavor mesons, suggesting that effects of the hot and dense nuclear matter created in heavy ion collisions contribute to its production. This measurement sets forth a promising new probe of the interplay of suppression and enhancement mechanisms in the production of heavy-flavor mesons in the quark-gluon plasma.

Inclusive transverse momentum spectra of primary charged particles in Pb-Pb collisions at $\sqrt{s_{_{\rm NN}}}$ = 2.76 TeV have been measured by the ALICE Collaboration at the LHC. The data are presented for central and peripheral collisions, corresponding to 0-5% and 70-80% of the hadronic Pb-Pb cross section. The measured charged particle spectra in $|\eta|<0.8$ and $0.3 < p_T < 20$ GeV/$c$ are compared to the expectation in pp collisions at the same $\sqrt{s_{\rm NN}}$, scaled by the number of underlying nucleon-nucleon collisions. The comparison is expressed in terms of the nuclear modification factor $R_{\rm AA}$. The result indicates only weak medium effects ($R_{\rm AA} \approx $ 0.7) in peripheral collisions. In central collisions, $R_{\rm AA}$ reaches a minimum of about 0.14 at $p_{\rm T}=6$-7GeV/$c$ and increases significantly at larger $p_{\rm T}$. The measured suppression of high-$p_{\rm T}$ particles is stronger than that observed at lower collision energies, indicating that a very dense medium is formed in central Pb-Pb collisions at the LHC.

The production of the $\psi(2S)$ charmonium state was measured with ALICE in Pb-Pb collisions at $\sqrt{s_{\rm NN}}=5.02$ TeV, in the dimuon decay channel. A significant signal was observed for the first time at LHC energies down to zero transverse momentum, at forward rapidity ($2.5<y<4$). The measurement of the ratio of the inclusive production cross sections of the $\psi(2S)$ and J/$\psi$ resonances is reported as a function of the centrality of the collisions and of transverse momentum, in the region $p_{\rm T}<12$ GeV/$c$. The results are compared with the corresponding measurements in pp collisions, by forming the double ratio $[\sigma^{\psi(2S)}/\sigma^{J/\psi}]_{\rm{Pb-Pb}}/[\sigma^{\psi(2S)}/\sigma^{J/\psi}]_{\rm{pp}}$. It is found that in Pb-Pb collisions the $\psi(2S)$ is suppressed by a factor of $\sim 2$ with respect to the J/$\psi$. The $\psi(2S)$ nuclear modification factor $R_{\rm AA}$ was also obtained as a function of both centrality and $p_{\rm T}$. The results show that the $\psi(2S)$ resonance yield is strongly suppressed in Pb-Pb collisions, by a factor up to $\sim 3$ with respect to pp. Comparisons of cross section ratios with previous SPS findings by the NA50 experiment and of $R_{\rm AA}$ with higher-$p_{\rm T}$ results at LHC energy are also reported. These results and the corresponding comparisons with calculations of transport and statistical models address questions on the presence and properties of charmonium states in the quark-gluon plasma formed in nuclear collisions at the LHC.

The production of K$^*$(892)$^\pm$ meson resonance is measured at midrapidity ($|y|<0.5$) in Pb-Pb collisions at $\sqrt{s_{\rm NN}}=5.02$ TeV using the ALICE detector at the LHC. The resonance is reconstructed via its hadronic decay channel K$^*$(892)$^\pm \rightarrow \rm{K^0_S \pi^\pm}$. The transverse momentum distributions are obtained for various centrality intervals in the $p_{\rm T}$ range of 0.4-16 GeV/$c$. The reported measurements of integrated yields, mean transverse momenta, and particle yield ratios are consistent with previous ALICE measurements for K$^*$(892)$^0$. The $p_{\rm T}$-integrated yield ratio 2K$^*$(892)$^\pm$/($\rm{K^+ + K^-}$) in central Pb-Pb collisions shows a significant suppression (9.3$\sigma$) relative to pp collisions. Thermal model calculations overpredict the particle yield ratio. Although both simulations consider the hadronic phase, only HRG-PCE accurately represents the measurements, whereas MUSIC+SMASH tends to overpredict them. These observations, along with the kinetic freeze-out temperatures extracted from the yields of light-flavored hadrons using the HRG-PCE model, indicate a finite hadronic phase lifetime, which increases towards central collisions. The $p_{\rm T}$-differential yield ratios 2K$^*$(892)$^\pm$/($\rm{K^+ + K^-}$) and 2K$^*$(892)$^\pm$/($\rm{\pi^+ + \pi^-}$) are suppressed by up to a factor of five at $p_{\rm T}<2$ GeV/$c$ in central Pb-Pb collisions compared to pp collisions at $\sqrt{s} =$ 5.02 TeV. Both particle ratios and are qualitatively consistent with expectations for rescattering effects in the hadronic phase. The nuclear modification factor shows a smooth evolution with centrality and is below unity at $p_{\rm T}>8$ GeV/$c$, consistent with measurements for other light-flavored hadrons. The smallest values are observed in most central collisions, indicating larger energy loss of partons traversing the dense medium.

The transverse momentum ($p_{\rm T}$) and centrality dependence of the nuclear modification factor $R_{\rm AA}$ of prompt and non-prompt J$/\psi$, the latter originating from the weak decays of beauty hadrons, have been measured by the ALICE collaboration in Pb$-$Pb collisions at $\sqrt{s_{\mathrm{NN}}}$ = 5.02 TeV. The measurements are carried out through the ${\rm e}^{+}{\rm e}^{-}$ decay channel at midrapidity ($|y| < 0.9$) in the transverse momentum region $1.5 < p_{\rm T} < 10$ GeV/$c$. Both prompt and non-prompt J$/\psi$ measurements indicate a significant suppression for $p_{\rm T} >$ 5 GeV/$c$, which becomes stronger with increasing collision centrality. The results are consistent with similar LHC measurements in the overlapping $p_{\rm T}$ intervals, and cover the kinematic region down to $p_{\rm T}$ = 1.5 GeV/$c$ at midrapidity, not accessible by other LHC experiments. The suppression of prompt J$/\psi$ in central and semicentral collisions exhibits a decreasing trend towards lower transverse momentum, described within uncertainties by models implementing J$/\psi$ production from recombination of c and $\overline{\rm c}$ quarks produced independently in different partonic scatterings. At high transverse momentum, transport models including quarkonium dissociation are able to describe the suppression for prompt J$/\psi$. For non-prompt J$/\psi$, the suppression predicted by models including both collisional and radiative processes for the computation of the beauty-quark energy loss inside the quark$-$gluon plasma is consistent with measurements within uncertainties.

Inclusive J/$\psi$ production is studied in Xe-Xe interactions at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\rm NN}}= 5.44$ TeV, using the ALICE detector at the CERN LHC. The J/$\psi$ meson is reconstructed via its decay into a muon pair, in the centre-of-mass rapidity interval $2.5<y<4$ and down to zero transverse momentum. In this Letter, the nuclear modification factors $R_{\rm AA}$ for inclusive J/$\psi$, measured in the centrality range 0-90% as well as in the centrality intervals 0-20% and 20-90% are presented. The $R_{\rm AA}$ values are compared to previously published results for Pb-Pb collisions at $\sqrt{s_{\rm NN}}= 5.02$ TeV and to the calculation of a transport model. A good agreement is found between Xe-Xe and Pb-Pb results as well as between data and the model.

A measurement of the production of prompt $\Lambda_{\rm c}^{+}$ baryons in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 5.02 $ TeV with the ALICE detector at the LHC is reported. The $\Lambda_{\rm c}^{+}$ and $\overline{\Lambda}_{\rm c}^{-}$ were reconstructed at midrapidity ($|y| < 0.5$) via the hadronic decay channel $\Lambda_{\rm c}^{+}\rightarrow {\rm p} {\rm K}_{\rm S}^{0}$ (and charge conjugate) in the transverse momentum and centrality intervals $6 < p_{\rm T} <12$ GeV/$c$ and 0-80%. The $\Lambda_{\rm c}^{+}$/D$^0$ ratio, which is sensitive to the charm quark hadronisation mechanisms in the medium, is measured and found to be larger than the ratio measured in minimum-bias pp collisions at $\sqrt{s} = 7$ TeV and in p-Pb collisions at $\sqrt{s_{\rm NN}} = 5.02 $ TeV. In particular, the values in p-Pb and Pb-Pb collisions differ by about two standard deviations of the combined statistical and systematic uncertainties in the common $p_{\rm T}$ interval covered by the measurements in the two collision system. The $\Lambda_{\rm c}^{+}$/D$^0$ ratio is also compared with model calculations including different implementations of charm quark hadronisation. The measured ratio is reproduced by models implementing a pure coalescence scenario, while adding a fragmentation contribution leads to an underestimation. The $\Lambda_{\rm c}^{+}$ nuclear modification factor, $R_{\rm AA}$, is also presented. The measured values of the $R_{\rm AA}$ of $\Lambda_{\rm c}^{+}$, D$_{\rm s}$ and non-strange D mesons are compatible within the combined statistical and systematic uncertainties. They show, however, a hint of a hierarchy $(R_{\rm AA}^{{\rm D}^{0}}<R_{\rm AA}^{{\rm D}_{\rm s}}<R_{\rm AA}^{\Lambda_{\rm c}^{+}})$, conceivable with a contribution of recombination mechanisms to charm hadron formation in the medium.

Inclusive $\Upsilon$(1S) and $\Upsilon$(2S) production have been measured in Pb-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair $\sqrt{s_{_{\rm NN}}}=5.02$ TeV, using the ALICE detector at the CERN LHC. The $\Upsilon$ mesons are reconstructed in the centre-of-mass rapidity interval $2.5<y<4$ and in the transverse-momentum range $p_{\rm T}<15$ GeV/$c$, via their decays to muon pairs. In this Letter, we present results on the inclusive $\Upsilon$(1S) nuclear modification factor $R_{\rm AA}$ as a function of collision centrality, transverse momentum and rapidity. The $\Upsilon$(1S) and $\Upsilon$(2S) $R_{\rm AA}$, integrated over the centrality range 0-90%, are $0.37 \pm 0.02 {\rm{(stat)}}\pm 0.03 {\rm{(syst)}}$ and $0.10 \pm 0.04 {\rm{(stat)}}\pm 0.02 {\rm{(syst)}}$, respectively, leading to a ratio $R_{\rm{AA}}^{\Upsilon(\rm2S)}/R_{\rm{AA}}^{\Upsilon(\rm1S)}$ of $0.28\pm0.12\text{(stat)}\pm0.06\text{(syst)}$. The observed $\Upsilon$(1S) suppression increases with the centrality of the collision and no significant variation is observed as a function of transverse momentum and rapidity.