The observation of the production of four top quarks in proton-proton collisions is reported, based on a data sample collected by the CMS experiment at a center-of-mass energy of 13 TeV in 2016-2018 at the CERN LHC and corresponding to an integrated luminosity of 138 fb$^{-1}$. Events with two same-sign, three, or four charged leptons (electrons and muons) and additional jets are analyzed. Compared to previous results in these channels, updated identification techniques for charged leptons and jets originating from the hadronization of b quarks, as well as a revised multivariate analysis strategy to distinguish the signal process from the main backgrounds, lead to an improved expected signal significance of 4.9 standard deviations above the background-only hypothesis. Four top quark production is observed with a significance of 5.6 standard deviations, and its cross section is measured to be 17.7 $^{+3.7}_{-3.5}$ (stat) $^{+2.3}_{-1.9}$ (syst) fb, in agreement with the available standard model predictions.

Differential production cross sections of J/$\psi$ and $\psi$(2S) charmonium and $\Upsilon$(nS) (n = 1, 2, 3) bottomonium states are measured in proton-proton collisions at $\sqrt{s} =$ 13 TeV, with data collected by the CMS detector at the LHC, corresponding to an integrated luminosity of 2.3 fb$^{-1}$ for the J/$\psi$ and 2.7 fb$^{-1}$ for the other mesons. The five quarkonium states are reconstructed in the dimuon decay channel, for dimuon rapidity $|y| <$ 1.2. The double-differential cross sections for each state are measured as a function of $y$ and transverse momentum, and compared to theoretical expectations. In addition, ratios are presented of cross sections for prompt $\psi$(2S) to J/$\psi$, $\Upsilon$(2S) to $\Upsilon$(1S), and $\Upsilon$(3S) to $\Upsilon$(1S) production.

The WZ production cross section in proton-proton collisions at sqrt(s) = 13 TeV is measured with the CMS experiment at the LHC using a data sample corresponding to an integrated luminosity of 2.3 inverse femtobarns. The measurement is performed in the leptonic decay modes WZ to l nu l' l', where l, l'= e, mu. The measured cross section for the range 60 < m[l'l'] < 120 GeV is sigma(pp to WZ) = 39.9 +/- 3.2 (stat) +2.9/-3.1 (syst) +/- 0.4 (theo) +/- 1.3 (lumi) pb, consistent with the standard model prediction.

The top quark pair production cross section is measured for the first time in proton-proton collisions at sqrt(s) = 13 TeV by the CMS experiment at the CERN LHC, using data corresponding to an integrated luminosity of 43 inverse picobarns. The measurement is performed by analyzing events with at least one electron and one muon of opposite charge, and at least two jets. The measured cross section is 746 +/- 58 (stat) +/- 53 (syst) +/- 36 (lumi) pb, in agreement with the expectation from the standard model.

The production of Z bosons associated with jets is measured in pp collisions at $\sqrt{s}$ = 13 TeV with data recorded with the CMS experiment at the LHC corresponding to an integrated luminosity of 36.3 fb$^{-1}$. The multiplicity of jets with transverse momentum $p_\mathrm{T}$$\gt$ 30 GeV is measured for different regions of the Z boson's $p_\mathrm{T}$(Z), from lower than 10 GeV to higher than 100 GeV. The azimuthal correlation $\Delta \phi$ between the Z boson and the leading jet, as well as the correlations between the two leading jets are measured in three regions of $p_\mathrm{T}$(Z). The measurements are compared with several predictions at leading and next-to-leading orders, interfaced with parton showers. Predictions based on transverse-momentum dependent parton distributions and corresponding parton showers give a good description of the measurement in the regions where multiple parton interactions and higher jet multiplicities are not important. The effects of multiple parton interactions are shown to be important to correctly describe the measured spectra in the low $p_\mathrm{T}$(Z) regions.

Protons consist of three valence quarks, two up-quarks and one down-quark, held together by gluons and a sea of quark-antiquark pairs. Collectively, quarks and gluons are referred to as partons. In a proton-proton collision, typically only one parton of each proton undergoes a hard scattering - referred to as single-parton scattering - leaving the remainder of each proton only slightly disturbed. Here, we report the study of double- and triple-parton scatterings through the simultaneous production of three J/$\psi$ mesons, which consist of a charm quark-antiquark pair, in proton-proton collisions recorded with the CMS experiment at the Large Hadron Collider. We observed this process - reconstructed through the decays of J/$\psi$ mesons into pairs of oppositely charged muons - with a statistical significance above five standard deviations. We measured the inclusive fiducial cross section to be 272 $^{+141}_{-104}$ (stat) $\pm$ 17 (syst) fb, and compared it to theoretical expectations for triple-J/$\psi$ meson production in single-, double- and triple-parton scattering scenarios. Assuming factorization of multiple hard-scattering probabilities in terms of single-parton scattering cross sections, double- and triple-parton scattering are the dominant contributions for the measured process.

A search for resonances decaying into a W boson and a radion, where the radion decays into two W bosons, is presented. The data analyzed correspond to an integrated luminosity of 138 fb$^{-1}$ recorded in proton-proton collisions with the CMS detector at $\sqrt{s} =$ 13 TeV. One isolated charged lepton is required, together with missing transverse momentum and one or two massive large-radius jets, containing the decay products of either two or one W bosons, respectively. No excess over the background estimation is observed. The results are combined with those from a complementary channel with an all-hadronic final state, described in an accompanying paper. Limits are set on parameters of an extended warped extra-dimensional model. These searches are the first of their kind at the LHC.

The differential cross sections for inclusive production of B+ hadrons are measured as a function of the B+ transverse momentum pT[B] and rapidity y[B] in pp collisions at a centre-of-mass energy of 13 TeV, using data collected by the CMS experiment that correspond to an integrated luminosity of 49.4 inverse picobarns. The measurement uses the exclusive decay channel B+ to J/psi K+, with J/psi mesons that decay to a pair of muons. The results show a reasonable agreement with theoretical calculations within the uncertainties.

A measurement of the cross section of the associated production of a single top quark and a W boson in final states with a muon or electron and jets in proton-proton collisions at $\sqrt{s}$ = 13 TeV is presented. The data correspond to an integrated luminosity of 36 fb$^{-1}$ collected with the CMS detector at the CERN LHC in 2016. A boosted decision tree is used to separate the tW signal from the dominant $\mathrm{t\bar{t}}$ background, whilst the subleading W+jets and multijet backgrounds are constrained using data-based estimates. This result is the first observation of the tW process in final states containing a muon or electron and jets, with a significance exceeding 5 standard deviations. The cross section is determined to be 89 $\pm$ 4 (stat) $\pm$ 12 (syst) pb, consistent with the standard model.

Three searches are presented for signatures of physics beyond the standard model (SM) in $\tau\tau$ final states in proton-proton collisions at the LHC, using a data sample collected with the CMS detector at $\sqrt{s}$ = 13 TeV, corresponding to an integrated luminosity of 138 fb$^{-1}$. Upper limits at 95% confidence level (CL) are set on the products of the branching fraction for the decay into $\tau$ leptons and the cross sections for the production of a new boson $\phi$, in addition to the H(125) boson, via gluon fusion (gg$\phi$) or in association with b quarks, ranging from $\mathcal{O}$(10 pb) for a mass of 60 GeV to 0.3 fb for a mass of 3.5 TeV each. The data reveal two excesses for gg$\phi$ production with local $p$-values equivalent to about three standard deviations at $m_\phi$ = 0.1 and 1.2 TeV. In a search for $t$-channel exchange of a vector leptoquark U$_1$, 95% CL upper limits are set on the dimensionless U$_1$ leptoquark coupling to quarks and $\tau$ leptons ranging from 1 for a mass of 1 TeV to 6 for a mass of 5 TeV, depending on the scenario. In the interpretations of the $M_\mathrm{h}^{125}$ and $M_\mathrm{h, EFT}^{125}$ minimal supersymmetric SM benchmark scenarios, additional Higgs bosons with masses below 350 GeV are excluded at 95% CL.