The production cross-sections of $\Upsilon(1S)$, $\Upsilon(2S)$ and $\Upsilon(3S)$ mesons in proton-proton collisions at $\sqrt{s}$= 13 TeV are measured with a data sample corresponding to an integrated luminosity of $277 \pm 11$ $\rm pb^{-1}$ recorded by the LHCb experiment in 2015. The $\Upsilon$ mesons are reconstructed in the decay mode $\Upsilon\to\mu^{+}\mu^{-}$. The differential production cross-sections times the dimuon branching fractions are measured as a function of the $\Upsilon$ transverse momentum, $p_{\rm T}$, and rapidity, $y$, over the range $0 < p_{\rm T}< 30$ GeV/c and $2.0 < y < 4.5$. The ratios of the cross-sections with respect to the LHCb measurement at $\sqrt{s}$= 8 TeV are also determined. The measurements are compared with theoretical predictions based on NRQCD.

The production cross-sections of $J/\psi$ mesons in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=5$ TeV are measured using a data sample corresponding to an integrated luminosity of $9.13\pm0.18~\text{pb}^{-1}$, collected by the LHCb experiment. The cross-sections are measured differentially as a function of transverse momentum, $p_{\text{T}}$, and rapidity, $y$, and separately for $J/\psi$ mesons produced promptly and from beauty hadron decays (nonprompt). With the assumption of unpolarised $J/\psi$ mesons, the production cross-sections integrated over the kinematic range $0<p_{\text{T}}<20~\text{GeV}/c$ and $2.0<y<4.5$ are $8.154\pm0.010\pm0.283~\mu\text{b}$ for prompt $J/\psi$ mesons and $0.820\pm0.003\pm0.034~\mu\text{b}$ for nonprompt $J/\psi$ mesons, where the first uncertainties are statistical and the second systematic. These cross-sections are compared with those at $\sqrt{s}=8$ TeV and $13$ TeV, and are used to update the measurement of the nuclear modification factor in proton-lead collisions for $J/\psi$ mesons at a centre-of-mass energy per nucleon pair of $\sqrt{s_{\text{NN}}}=5$ TeV. The results are compared with theoretical predictions.

A precision measurement of the $Z$ boson production cross-section at $\sqrt{s} = 13$ TeV in the forward region is presented, using $pp$ collision data collected by the LHCb detector, corresponding to an integrated luminosity of 5.1 fb$^{-1}$. The production cross-section is measured using $Z\rightarrow\mu^+\mu^-$ events within the fiducial region defined as pseudorapidity $2.0<\eta<4.5$ and transverse momentum $p_{T}>20$ GeV/$c$ for both muons and dimuon invariant mass $60<M_{\mu\mu}<120$ GeV/$c^2$. The integrated cross-section is determined to be $\sigma (Z \rightarrow \mu^+ \mu^-)$ = 196.4 $\pm$ 0.2 $\pm$ 1.6 $\pm$ 3.9~pb, where the first uncertainty is statistical, the second is systematic, and the third is due to the luminosity determination. The measured results are in agreement with theoretical predictions within uncertainties.

Forward top quark pair production is studied in $pp$ collisions in the $\mu eb$ final state using a data sample corresponding to an integrated luminosity of 1.93 fb$^{-1}$ collected with the LHCb experiment at a centre-of-mass energy of 13 TeV. The cross-section is measured in a fiducial region where both leptons have a transverse momentum greater than 20 GeV and a pseudorapidity between 2.0 and 4.5. The quadrature sum of the azimuthal separation and the difference in pseudorapidities, denoted $\Delta R$, between the two leptons must be larger than 0.1. The $b$-jet axis is required to be separated from both leptons by a $\Delta R$ of 0.5, and to have a transverse momentum in excess of 20 GeV and a pseudorapidity between 2.2 and 4.2. The cross-section is measured to be $$\sigma_{t\bar{t}}= 126\pm19\,(\mathrm{stat})\pm16\,(\mathrm{syst})\pm5\,(\mathrm{lumi})\,\,\mathrm{ fb}$$ where the first uncertainty is statistical, the second is systematic, and the third is due to the luminosity determination. The measurement is compatible with the Standard Model prediction.

The differential cross-section of prompt inclusive production of long-lived charged particles in proton-proton collisions is measured using a data sample recorded by the LHCb experiment at a centre-of-mass energy of ${\sqrt{s} = 13\,\mathrm{TeV}}$. The data sample, collected with an unbiased trigger, corresponds to an integrated luminosity of ${5.4\,\mathrm{nb}^{-1}}$. The differential cross-section is measured as a function of transverse momentum and pseudorapidity in the ranges ${p_\mathrm{T} \in [0.08, 10)\,\mathrm{GeV}\,c^{-1}}$ and ${\eta \in [2.0, 4.8)}$ and is determined separately for positively and negatively charged particles. The results are compared with predictions from various hadronic-interaction models.

The inclusive $b \bar{b}$- and $c \bar{c}$-dijet production cross-sections in the forward region of $pp$ collisions are measured using a data sample collected with the LHCb detector at a centre-of-mass energy of 13 TeV in 2016. The data sample corresponds to an integrated luminosity of 1.6 fb$^{-1}$. Differential cross-sections are measured as a function of the transverse momentum and of the pseudorapidity of the leading jet, of the rapidity difference between the jets, and of the dijet invariant mass. A fiducial region for the measurement is defined by requiring that the two jets originating from the two $b$ or $c$ quarks are emitted with transverse momentum greater than 20 GeV$/c$, pseudorapidity in the range $2.2 < \eta < 4.2$, and with a difference in the azimuthal angle between the two jets greater than 1.5. The integrated $b \bar{b}$-dijet cross-section is measured to be $53.0 \pm 9.7$ nb, and the total $c \bar{c}$-dijet cross-section is measured to be $73 \pm 16$ nb. The ratio between $c \bar{c}$- and $b \bar{b}$-dijet cross-sections is also measured and found to be $1.37 \pm 0.27$. The results are in agreement with theoretical predictions at next-to-leading order.

Measurements of the cross-section for producing \bquark quarks in the reaction $pp\to b\bar{b} X$ are reported in 7 and 13 TeV collisions at the LHC as a function of the pseudorapidity $\eta$ in the range $2<\eta<5$ covered by the acceptance of the LHCb experiment. The measurements are done using semileptonic decays of $b$-flavored hadrons decaying into a ground-state charmed hadron in association with a muon. The cross-sections in the covered $\eta$ range are $72.0\pm 0.3\pm6.8~\mu$b and $144\pm 1\pm 21~\mu$b for 7 and 13 TeV. The ratio is $2.00\pm0.02\pm0.26$, where the quoted uncertainties are statistical and systematic, respectively. The agreement with theoretical expectation is good at 7 TeV, but differs somewhat at 13 TeV. The measured ratio of cross-sections is larger at lower $\eta$ than the model prediction.

Production cross-sections of prompt charm mesons are measured using data from $pp$ collisions at the LHC at a centre-of-mass energy of $5\,$TeV. The data sample corresponds to an integrated luminosity of $8.60\pm0.33\,$pb$^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^0$, $D^+$, $D_s^+$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\text{T}}$, and rapidity, $y$. They cover the rapidity range $2.0<y<4.5$ and transverse momentum ranges $0 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D^0$ and $D^+$ and $1 < p_{\text{T}} < 10\, \text{GeV}/c$ for $D_s^+$ and $D^{*+}$ mesons. The inclusive cross-sections for the four mesons, including charge-conjugate states, within the range of $1 < p_{\text{T}} < 8\, \text{GeV}/c$ are determined to be \sigma(pp\rightarrow D^0 X) = 1004 \pm 3 \pm 54\,\mu\text{b} \sigma(pp\rightarrow D^+ X) = 402 \pm 2 \pm 30\,\mu\text{b} \sigma(pp\rightarrow D_s^+ X) = 170 \pm 4 \pm 16\,\mu\text{b} \sigma(pp\rightarrow D^{*+} X)= 421 \pm 5 \pm 36\,\mu\text{b} where the uncertainties are statistical and systematic, respectively.

The production of $J/\psi$ mesons in proton-proton collisions at a centre-of-mass energy of $\sqrt{s}=13$ TeV is studied with the \lhcb detector. Cross-section measurements are performed as a function of the transverse momentum $p_\mathrm{T}$ and the rapidity $y$ of the $J/\psi$ meson in the region $p_\mathrm{T}<14\mathrm{GeV}/c$ and $2.0<y<4.5$, for both prompt $J/\psi$ mesons and $J/\psi$ mesons from $b$-hadron decays. The production cross-sections integrated over the kinematic coverage are $15.03\pm 0.03\pm 0.94$ $\mu$b for prompt $J/\psi$ and $2.25\pm 0.01\pm 0.14$ $\mu$b for $J/\psi$ from $b$-hadron decays, assuming zero polarization of the $J/\psi$ meson. The first uncertainties are statistical and the second systematic. The cross-section reported for $J/\psi$ mesons from $b$-hadron decays is used to extrapolate to a total $b\bar{b}$ cross-section. The ratios of the cross-sections with respect to $\sqrt{s}=8$ TeV are also determined.

Production cross-sections of prompt charm mesons are measured with the first data from $pp$ collisions at the LHC at a centre-of-mass energy of $13\,\mathrm{TeV}$. The data sample corresponds to an integrated luminosity of $4.98 \pm 0.19\,\mathrm{pb}^{-1}$ collected by the LHCb experiment. The production cross-sections of $D^{0}$, $D^{+}$, $D_{s}^{+}$, and $D^{*+}$ mesons are measured in bins of charm meson transverse momentum, $p_{\mathrm{T}}$, and rapidity, $y$, and cover the range $0 < p_{\mathrm{T}} < 15\,\mathrm{GeV}/c$ and $2.0 < y < 4.5$. The inclusive cross-sections for the four mesons, including charge conjugation, within the range of $1 < p_{\mathrm{T}} < 8\,\mathrm{GeV}/c$ are found to be \begin{equation} \sigma(pp \to D^{0} X) = 2072 \pm 2 \pm 124\,\mu\mathrm{b}\\ \sigma(pp \to D^{+} X) = 834 \pm 2 \pm \phantom{1}78\,\mu\mathrm{b}\\ \sigma(pp \to D_{s}^{+} X) = 353 \pm 9 \pm \phantom{1}76\,\mu\mathrm{b}\\ \sigma(pp \to D^{*+} X) = 784 \pm 4 \pm \phantom{1}87\,\mu\mathrm{b} \end{equation} where the uncertainties are due to statistical and systematic uncertainties, respectively.