The $B_\mathrm{c}^+$ meson is observed for the first time in heavy ion collisions. Data from the CMS detector are used to study the production of the $B_\mathrm{c}^+$ meson in lead-lead (PbPb) and proton-proton (pp) collisions at a center-of-mass energy per nucleon pair of $\sqrt{s_{\mathrm{NN}}} =$ 5.02 TeV, via the $B_\mathrm{c}^+ \to (J/\psi\to\mu^+\mu^-)\mu^+\nu_\mu$ decay. The $B_\mathrm{c}^+$ nuclear modification factor, derived from the PbPb-to-pp ratio of production cross sections, is measured in two bins of the trimuon transverse momentum and of the PbPb collision centrality. The B$_\mathrm{c}^+$ meson is shown to be less suppressed than quarkonia and most of the open heavy-flavor mesons, suggesting that effects of the hot and dense nuclear matter created in heavy ion collisions contribute to its production. This measurement sets forth a promising new probe of the interplay of suppression and enhancement mechanisms in the production of heavy-flavor mesons in the quark-gluon plasma.

The production of prompt $\rm \Lambda_{\rm c}^{+}$ baryons at midrapidity ($|y|<0.5$) was measured in central (0-10%) and mid-central (30-50%) Pb-Pb collisions at the center-of-mass energy per nucleon-nucleon pair $\sqrt{s_{\rm NN}} = 5.02$ TeV with the ALICE detector. The results are more precise, more differential in centrality, and reach much lower transverse momentum ($p_{\rm T}=1$ GeV/$c$) with respect to previous measurements performed by the ALICE, STAR, and CMS Collaborations in nucleus-nucleus collisions, allowing for an extrapolation down to $p_{\rm T}=0$. The $p_{\rm T}$-differential $\rm \Lambda_{\rm c}^{+}$/D$^0$ production ratio is enhanced with respect to the pp measurement for $4<p_{\rm T}<8$ GeV/$c$ by 3.7 standard deviations ($\sigma$), while the $p_{\rm T}$-integrated ratios are compatible within 1$\sigma$. The observed trend is similar to that observed in the strange sector for the $\Lambda/$K$^0_{\rm S}$ ratio. Model calculations including coalescence or statistical hadronization for charm-hadron formation are compared with the data.

The production yield and angular anisotropy of prompt ${D_s^+}$ mesons were measured as a function of transverse momentum ($p_{ T}$) in Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{ NN}} = 5.02$ TeV collected with the ALICE detector at the LHC. ${D_s^+}$ mesons and their charge conjugates were reconstructed at midrapidity ($|y|<0.5$) from their hadronic decay channel ${D_s^+ \to \phi \pi^+}$, with ${\phi \to K^-K^+}$, in the $p_{ T}$ intervals $2<p_{ T}<50$ GeV/$c$ and $2<p_{ T}<36$ GeV/$c$ for the 0-10% and 30-50% centrality intervals. For $p_{ T}>10$ GeV/$c$, the measured ${D_s^+}$-meson nuclear modification factor $R_{ AA}$ is consistent with the one of non-strange D mesons within uncertainties, while at lower $p_{ T}$ a hint for a ${D_s^+}$-meson $R_{ AA}$ larger than that of non-strange D mesons is seen. The enhanced production of ${D_s^+}$ relative to non-strange D mesons is also studied by comparing the $p_{ T}$-dependent ${D_s^+/D^0}$ production yield ratios in Pb-Pb and in pp collisions. The ratio measured in Pb-Pb collisions is found to be on average higher than that in pp collisions in the interval $2<p_{ T} <8$ GeV/$c$ with a significance of 2.3$\sigma$ and 2.4$\sigma$ for the 0-10% and 30-50% centrality intervals. The azimuthal anisotropy coefficient $v_2$ of prompt ${D_s^+}$ mesons was measured in Pb-Pb collisions in the 30-50% centrality interval and is found to be compatible with that of non-strange D mesons. The main features of the measured $R_{ AA}$, ${D_s^+/D^0}$ ratio, and $v_2$ as a function of $p_{ T}$ are described by theoretical calculations of charm-quark transport in a hydrodynamically expanding quark-gluon plasma including hadronisation via charm-quark recombination with light quarks from the medium. The $p_{ T}$-integrated production yield of ${D_s^+}$ mesons is compatible with the prediction of the statistical hadronisation model.

Heavy-flavour hadron production provides information about the transport properties and microscopic structure of the quark-gluon plasma created in ultra-relativistic heavy-ion collisions. A measurement of the muons from semileptonic decays of charm and bottom hadrons produced in Pb+Pb and $pp$ collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV with the ATLAS detector at the Large Hadron Collider is presented. The Pb+Pb data were collected in 2015 and 2018 with sampled integrated luminosities of $208~\mathrm{\mu b}^{-1}$ and $38~\mathrm{\mu b^{-1}}$, respectively, and $pp$ data with a sampled integrated luminosity of $1.17~\mathrm{pb}^{-1}$ were collected in 2017. Muons from heavy-flavour semileptonic decays are separated from the light-flavour hadronic background using the momentum imbalance between the inner detector and muon spectrometer measurements, and muons originating from charm and bottom decays are further separated via the muon track's transverse impact parameter. Differential yields in Pb+Pb collisions and differential cross sections in $pp$ collisions for such muons are measured as a function of muon transverse momentum from 4 GeV to 30 GeV in the absolute pseudorapidity interval $|\eta| < 2$. Nuclear modification factors for charm and bottom muons are presented as a function of muon transverse momentum in intervals of Pb+Pb collision centrality. The measured nuclear modification factors quantify a significant suppression of the yields of muons from decays of charm and bottom hadrons, with stronger effects for muons from charm hadron decays.

Jet production in lead-lead (PbPb) and proton-proton (pp) collisions at a nucleon-nucleon center-of-mass energy of 5.02 TeV is studied with the CMS detector at the LHC, using PbPb and pp data samples corresponding to integrated luminosities of 404 $\mu$b$^{-1}$ and 27.4 pb$^{-1}$, respectively. Jets with different areas are reconstructed using the anti-$k_\mathrm{T}$ algorithm by varying the distance parameter $R$. The measurements are performed using jets with transverse momenta ($p_\mathrm{T}$) greater than 200 GeV and in a pseudorapidity range of $|\eta|$$\lt$ 2. To reveal the medium modification of the jet spectra in PbPb collisions, the properly normalized ratio of spectra from PbPb and pp data is used to extract jet nuclear modification factors as functions of the PbPb collision centrality, $p_\mathrm{T}$ and, for the first time, as a function of $R$ up to 1.0. For the most central collisions, a strong suppression is observed for high-$p_\mathrm{T}$ jets reconstructed with all distance parameters, implying that a significant amount of jet energy is scattered to large angles. The dependence of jet suppression on $R$ is expected to be sensitive to both the jet energy loss mechanism and the medium response, and so the data are compared to several modern event generators and analytic calculations. The models considered do not fully reproduce the data.

The first measurements of the production of muons and electrons from heavy-flavour hadron decays in Xe-Xe collisions at $\sqrt{s_{\rm NN}}$ = 5.44 TeV, using the ALICE detector at the LHC, are reported. The measurement of the nuclear modification factor $R_{\rm AA}$ is performed as a function of transverse momentum $p_{\rm T}$ in several centrality classes at forward rapidity ($2.5 < y <4$) and midrapidity ($\vert y \vert < 0.8$) for muons and electrons from heavy-flavour hadron decays, respectively. A suppression by a factor up to about 2.5 compared to the binary-scaled pp reference is observed in central collisions at both central and forward rapidities. The $R_{\rm AA}$ of muons from heavy-flavour hadron decays is compared to previous measurements in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV. When the nuclear modification factors are compared in the centrality classes 0-10% for Xe-Xe collisions and 10-20% for Pb-Pb collisions, which have similar charged-particle multiplicity density, a similar suppression, with $R_{\rm AA} \sim 0.4$ in the $p_{\rm T}$ interval $4 < p_{\rm T} < 8$ GeV/$c$, is observed. The comparison of the measured $R_{\rm AA}$ values in the two collision systems brings new insights on the properties of the quark-gluon plasma by investigating the system-size and path-length dependence of medium-induced parton energy loss. The results of muons and electrons from heavy-flavour hadron decays provide new constraints to model calculations.

The production of $\Upsilon$ mesons in Pb-Pb collisions at a centre-of-mass energy per nucleon pair $\sqrt{s_{\rm NN}}$ = 5 TeV is measured with the muon spectrometer of the ALICE detector at the LHC. The yields as well as the nuclear modification factors are determined in the forward rapidity region $2.5<y<4.0$, as a function of rapidity, transverse momentum and collision centrality. The results show that the production of the $\Upsilon$(1S) meson is suppressed by a factor of about three with respect to the production in proton-proton collisions. For the first time, a significant signal for the $\Upsilon$(2S) meson is observed at forward rapidity, indicating a suppression stronger by about a factor 2-3 with respect to the ground state. The measurements are compared with transport, hydrodynamic, comover and statistical hadronisation model calculations.

Measurements of the production of muons from heavy-flavour hadron decays in Pb$-$Pb collisions at $\sqrt{s_{\rm NN}}$ = $5.02$ and $2.76$ TeV using the ALICE detector at the LHC are reported. The nuclear modification factor $R_{\rm AA}$ at $\sqrt{s_{\rm NN}}$ = 5.02 TeV is measured at forward rapidity ($2.5 < y <4$) as a function of transverse momentum $p_{\rm T}$ in central, semi-central, and peripheral collisions over a wide $p_{\rm T}$ interval, $3 < p_{\rm T} < 20$ GeV/$c$, in which muons from beauty-hadron decays are expected to take over from charm as the dominant source at high $p_{\rm T}$ ($p_{\rm T} > 7$ GeV/$c$). The $R_{\rm AA}$ shows an increase of the suppression of the yields of muons from heavy-flavour hadron decays with increasing centrality. A suppression by a factor of about three is observed in the $10\%$ most central collisions. The $R_{\rm AA}$ at $\sqrt{s_{\rm NN}}$ = 5.02 is similar to that at 2.76 TeV. The precise $R_{\rm AA}$ measurements have the potential to distinguish between model predictions implementing different mechanisms of parton energy loss in the high-density medium formed in heavy-ion collisions. They place important constraints for the understanding of the heavy-quark interaction with the hot and dense QCD medium.

The transverse energy ($E_\mathrm{T}^{\gamma}$) spectra of photons isolated from other particles are measured using proton-proton (pp) and lead-lead (PbPb) collisions at the LHC at $\sqrt{s_\mathrm{NN}} =$ 5.02 TeV with integrated luminosities of 27.4 pb$^{-1}$and 404 $\mu$b$^{-1}$ for pp and PbPb data, respectively. The results are presented for photons with 25 $<$ $E_\mathrm{T}^{\gamma}$ $<$ 200 GeV in the pseudorapidity range $|\eta|$ $<$ 1.44, and for different centrality intervals for PbPb collisions. Photon production in PbPb collisions is consistent with that in pp collisions scaled by the number of binary nucleon-nucleon collisions, demonstrating that photons do not interact with the quark-gluon plasma. Therefore, isolated photons can provide information about the initial energy of the associated parton in photon+jet measurements. The results are compared with predictions from the next-to-leading-order JETPHOX generator for different parton distribution functions (PDFs) and nuclear PDFs (nPDFs). The comparisons can help to constrain the nPDFs global fits.

The inclusive J/$\psi$ meson production in Pb-Pb collisions at a center-of-mass energy per nucleon-nucleon collision of $\sqrt{s_{\rm NN}}$ = 5.02 TeV at midrapidity ($|y|$ < 0.9) is reported by the ALICE Collaboration. The measurements are performed in the dielectron decay channel, as a function of event centrality and J/$\psi$ transverse momentum $p_{\rm T}$, down to $p_{\rm T}$ = 0 GeV/$c$. The J/$\psi$ mean transverse momentum $\langle p_{\rm T} \rangle$ and $r_{\rm AA}$ ratio, defined as $\langle p^{\rm 2}_{\rm T} \rangle_{\rm PbPb}/\langle p^{\rm 2}_{\rm T} \rangle_{\rm pp}$, are evaluated. Both observables show a centrality dependence decreasing towards central (head-on) collisions. The J/$\psi$ nuclear modification factor $R_{\rm AA}$ exhibits a strong $p_{\rm T}$ dependence with a large suppression at high $p_{\rm T}$ and an increase to unity for decreasing $p_{\rm T}$. When integrating over the measured momentum range $p_{\rm T}$ < 10 GeV/$c$, the J/$\psi$ $R_{\rm AA}$ shows a weak centrality dependence. Each measurement is compared with results at lower center-of-mass energies and with ALICE measurements at forward rapidity, as well as to theory calculations. All reported features of the J/$\psi$ production at low $p_{\rm T}$ are consistent with a dominant contribution to the J/$\psi$ yield originating from charm quark (re)combination.